Salinas Maria, López-Garrigós Maite, Flores Emilio, Leiva-Salinas Carlos
Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, Spain.
Department of Biochemistry and Molecular Pathology, Universidad Miguel Hernandez, Elche, Spain.
Lab Med. 2017 Aug 1;48(3):271-276. doi: 10.1093/labmed/lmx051.
To compare the ratios of requests of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) and urea to creatinine (Crea); to investigate the variability among regions and to calculate the potential savings if a target is reached.
Laboratories were invited to fill out a registration form on the number of AST, ALT, Urea and Crea requested in 2014, and to provide the reagent price of urea and AST. AST:ALT and Urea:Crea were calculated and compared; also compared were potential savings if each laboratory would have reached the target. Results: A significant difference was found among regions in Urea:Crea. Twenty-one laboratories reached the goal in AST:ALT, and 6 in Urea:Crea. The potential savings if each indicator would have reached the target would have been $553,827 and $745,184, respectively.
Variability was found in AST:ALT and Urea:Crea, which resulted in a significant unnecessary financial burden and suggests the need to promote the optimal requesting rate.
比较天冬氨酸氨基转移酶（AST）与丙氨酸氨基转移酶（ALT）的检测申请比率以及尿素与肌酐（Crea）的检测申请比率；调查各地区之间的差异，并计算若达到目标可节省的费用。
邀请各实验室填写一份关于2014年AST、ALT、尿素和Crea检测申请数量的登记表，并提供尿素和AST的试剂价格。计算并比较AST:ALT和尿素:Crea；同时比较各实验室若达到目标可节省的费用。结果：各地区在尿素:Crea方面存在显著差异。21个实验室在AST:ALT方面达到目标，6个实验室在尿素:Crea方面达到目标。若每个指标都达到目标，可节省的费用分别为553,827美元和745,184美元。
在AST:ALT和尿素:Crea方面发现存在差异，这导致了显著的不必要财务负担，表明需要提高最佳申请率。
