Tedesco Nicholas S, Van Horn Alexandra L, Henshaw Robert M
Orthopedics. 2017 Nov 1;40(6):e964-e970. doi: 10.3928/01477447-20170918-04. Epub 2017 Sep 22.
Intercalary endoprosthetic reconstruction following diaphyseal resection of osseous tumors offers functional advantages through preservation of native joints adjacent to the resected defect. Use of such implants is restricted by the amount of bone available for stem fixation adjacent to the defect. This study aimed to determine whether short osseous segment fixation with acceptable outcomes and complication rate can be reliably achieved with a customized intercalary endoprosthesis following extended diaphysectomy. A retrospective review of prospectively collected data was performed on 6 patients receiving customized anchor plugs for short segment fixation with a double compressive osseointegration intercalary implant to reconstruct segmental defects. Five of the implants were augmented with cement to support fixation in metaphyseal bone. Patient age at surgery ranged from 12 to 86 years. At mean follow-up of 39 months, mean Musculoskeletal Tumor Society functional score was 26.3, with 5 of 6 patients achieving scores of 27 or greater. Stable fixation was achieved in all patients, with the shortest segment of bone 3.7 cm in length. Three mechanical implant failures requiring revision surgery occurred. No patient required revision of the entire implant, secondary adjacent joint replacement, or secondary amputation. No patient exhibited aseptic loosening, and no case was complicated by infection. Excellent functional outcomes were seen with follow-up out to 9 years. This suggests that cement-augmented double compressive osseointegration intercalary endoprosthetic reconstruction can extend the benefits of intercalary replacement to many patients who otherwise might require adjacent joint or physeal sacrifice. However, patients should be counseled on the high risk of implant failure with subsequent need for revision surgery. [Orthopedics. 2017; 40(6):e964-e970.].
骨干骨肿瘤切除术后采用骨端假体置换重建,通过保留切除缺损相邻的天然关节,具有功能上的优势。此类植入物的使用受到缺损附近可用于柄部固定的骨量的限制。本研究旨在确定在扩大骨干切除术后,使用定制的骨端假体能否可靠地实现短骨段固定,并获得可接受的疗效和并发症发生率。对6例接受定制锚定栓进行短节段固定的患者进行了回顾性研究,这些患者采用双压缩骨整合骨端植入物重建节段性缺损。其中5枚植入物用骨水泥增强,以支持在干骺端骨中的固定。手术时患者年龄为12至86岁。平均随访39个月时,肌肉骨骼肿瘤学会功能评分平均为26.3分,6例患者中有5例评分达到27分或更高。所有患者均实现了稳定固定,最短的骨段长度为3.7厘米。发生了3例需要翻修手术的机械性植入物失败。没有患者需要翻修整个植入物、二期相邻关节置换或二期截肢。没有患者出现无菌性松动,也没有病例并发感染。随访至9年时,观察到了优异的功能结果。这表明骨水泥增强的双压缩骨整合骨端假体置换重建可将骨端置换的益处扩展到许多原本可能需要牺牲相邻关节或骨骺的患者。然而,应告知患者植入物失败及随后需要翻修手术的高风险。[《骨科》。2017;40(6):e964 - e970。]