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骨干骨肿瘤的中间段人工关节置换重建术。

Intercalary endoprosthetic reconstruction for diaphyseal bone tumours.

作者信息

Ahlmann E R, Menendez L R

机构信息

Keck School of Medicine, University of Southern California Medical Center, 1200 N. State Street, GNH 3900, Los Angeles, California 90033, USA.

出版信息

J Bone Joint Surg Br. 2006 Nov;88(11):1487-91. doi: 10.1302/0301-620X.88B11.18038.

Abstract

Custom-made intercalary endoprostheses may be used for the reconstruction of diaphyseal defects following the resection of bone tumours. The aim of this study was to determine the survival of intercalary endoprostheses with a lap joint design, and to evaluate the clinical results, complications and functional outcome. We retrospectively reviewed six consecutive patients, three of whom underwent limb salvage with intercalary endoprostheses of the tibia, two of the femur, and one of the humerus. Their mean age was 42 years (28 to 64). The mean follow-up was 21.6 months (9 to 58). The humeral prosthesis required revision at 14 months owing to aseptic loosening. There were no implant-related failures. Musculoskeletal Tumour Society functional outcome scores indicated that patients achieved 90% of premorbid function. Custom intercalary endoprostheses result in reconstructions comparable with, if not better than, those of allografts. Using this design of implant reduces the incidence of early complications and difficulties experienced with previous versions.

摘要

定制的节段性内置假体可用于骨肿瘤切除术后骨干缺损的重建。本研究的目的是确定采用搭接关节设计的节段性内置假体的生存率,并评估临床结果、并发症和功能结局。我们回顾性分析了连续6例患者,其中3例行胫骨节段性内置假体保肢手术,2例行股骨节段性内置假体保肢手术,1例行肱骨节段性内置假体保肢手术。他们的平均年龄为42岁(28至64岁)。平均随访时间为21.6个月(9至58个月)。肱骨假体因无菌性松动在14个月时需要翻修。没有与植入物相关的失败病例。肌肉骨骼肿瘤学会的功能结局评分表明患者实现了病前功能的90%。定制节段性内置假体的重建效果即使不比同种异体移植更好,也与之相当。采用这种植入物设计可降低早期并发症的发生率以及以往版本所遇到的困难。

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