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Fibrotic progression in Polycythemia vera is associated with early concomitant driver-mutations besides JAK2.

作者信息

Bartels S, Faisal M, Büsche G, Schlue J, Kreipe H, Lehmann U

机构信息

Institute of Pathology, Hannover Medical School, Hannover, Germany.

出版信息

Leukemia. 2018 Feb;32(2):556-558. doi: 10.1038/leu.2017.298. Epub 2017 Sep 22.

DOI:10.1038/leu.2017.298
PMID:28935989
Abstract
摘要

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Primary myelofibrosis: Older age and high JAK2V617F allele burden are associated with elevated plasma high-sensitivity C-reactive protein levels and a phenotype of progressive disease.原发性骨髓纤维化：老年及高JAK2V617F等位基因负荷与血浆高敏C反应蛋白水平升高及疾病进展表型相关。
Leuk Res. 2017 Sep;60:18-23. doi: 10.1016/j.leukres.2017.06.004. Epub 2017 Jun 7.
2
A clinical-molecular prognostic model to predict survival in patients with post polycythemia vera and post essential thrombocythemia myelofibrosis.一个临床-分子预后模型，用于预测真性红细胞增多症后和特发性血小板增多症后骨髓纤维化患者的生存情况。
Leukemia. 2017 Dec;31(12):2726-2731. doi: 10.1038/leu.2017.169. Epub 2017 May 31.
3
血浆来源的细胞外囊泡的特定宿主/微生物特征与真性红细胞增多症中的血栓形成和骨髓纤维化相关。
Cancers (Basel). 2021 Oct 2;13(19):4968. doi: 10.3390/cancers13194968.
4
The Role of Megakaryocytes in Myelofibrosis.巨核细胞在骨髓纤维化中的作用。
Hematol Oncol Clin North Am. 2021 Apr;35(2):191-203. doi: 10.1016/j.hoc.2020.11.004. Epub 2021 Jan 11.
5
Next Generation Sequencing in MPNs. Lessons from the Past and Prospects for Use as Predictors of Prognosis and Treatment Responses.骨髓增殖性肿瘤中的下一代测序。过去的经验教训以及用作预后和治疗反应预测指标的前景。
Cancers (Basel). 2020 Aug 6;12(8):2194. doi: 10.3390/cancers12082194.
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Cells. 2019 Aug 8;8(8):854. doi: 10.3390/cells8080854.
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