Dhafiri Yousef, Al Rubaie Khalid, Kirat Omar, May William N, Nguyen Quan D, Kozak Igor
King Khaled Eye Specialist Hospital, Al-Arouba, Riyadh 11462, Kingdom of Saudi Arabia.
Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
Middle East Afr J Ophthalmol. 2017 Apr-Jun;24(2):109-112. doi: 10.4103/meajo.MEAJO_331_16.
The purpose of this study is to describe an association of unilateral multifocal choroiditis (MFC), retinal vasculitis, optic neuropathy, and bilateral keratoconus in a young Saudi male. A 27-year-old male patient with stable bilateral keratoconus presented with a painless vision loss in his left eye. Ophthalmic examinations revealed multiple foci of idiopathic chorioretinitis, retinal vasculitis, and mild optic disc leakage on fluorescein angiography, all of which resolved on systemic therapy with mycophenolate mofetil and prednisone after 3 months. Systemic medication was stopped after 8 months. One year after presentation, patient's visual acuity has improved and remained stable. Systemic immunomodulatory therapy can be effective in managing and leading to resolution of MFC, retinal vasculitis, and optic disc leak in young patients.
本研究的目的是描述一名年轻沙特男性患者单侧多灶性脉络膜炎(MFC)、视网膜血管炎、视神经病变和双侧圆锥角膜之间的关联。一名患有稳定双侧圆锥角膜的27岁男性患者左眼出现无痛性视力丧失。眼科检查发现特发性脉络膜视网膜炎的多个病灶、视网膜血管炎以及荧光素血管造影显示的轻度视盘渗漏,所有这些在使用霉酚酸酯和泼尼松进行全身治疗3个月后均得到缓解。8个月后停用全身药物。就诊一年后,患者的视力有所改善并保持稳定。全身免疫调节治疗对于管理年轻患者的MFC、视网膜血管炎和视盘渗漏并使其得到缓解可能是有效的。