From the Department of Anesthesiology, University of Virginia, Charlottesville, VA.
Reg Anesth Pain Med. 2017 Nov/Dec;42(6):698-708. doi: 10.1097/AAP.0000000000000663.
Chronic pain following median sternotomy is common after cardiac surgery. If left untreated, chronic sternal pain can reduce quality of life, affecting sleep, mood, activity level, and overall satisfaction. This has a significant societal effect given the large number of cardiac surgeries annually. Although a number of pathophysiologic processes and risk factors are assumed to contribute, the exact cause and major risk factors remain unknown. Moreover, the treatment of chronic poststernotomy pain is often inadequate, relying on opioids and other medications that provide minimal benefit to the patient and have significant adverse effects. Indeed, little is known regarding the prevention of chronic pain development following sternotomy. This review aims to present the current, limited data regarding the incidence, risk factors, treatment, and prevention of chronic poststernotomy pain and to identify areas of future research to improve management of this common complaint following cardiac surgery.
胸骨正中切开术后的慢性疼痛在心脏手术后很常见。如果不进行治疗,慢性胸骨疼痛会降低生活质量,影响睡眠、情绪、活动水平和整体满意度。鉴于每年有大量的心脏手术,这会对社会产生重大影响。尽管有许多病理生理过程和危险因素被认为与之相关,但确切的原因和主要危险因素仍不清楚。此外,慢性胸骨切开术后疼痛的治疗往往不充分,依赖于阿片类药物和其他药物,这些药物对患者的益处很小,且有显著的不良反应。事实上,对于胸骨切开术后慢性疼痛发展的预防知之甚少。本综述旨在介绍目前关于胸骨切开术后慢性疼痛的发生率、危险因素、治疗和预防的有限数据,并确定未来研究的领域,以改善心脏手术后这种常见并发症的管理。