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皮埃尔·罗宾序列征患者腭裂修复术后的呼吸并发症:手术考量

Postoperative Respiratory Complications After Cleft Palate Closure in Patients With Pierre Robin Sequence: Operative Considerations.

作者信息

Opdenakker Yasmin, Swennen Gwen, Pottel Lies, Abeloos Johan, Nagy Krisztián

机构信息

*Division of Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Hospital †Bruges Cleft and Craniofacial Center, Bruges, Belgium ‡Cleft Service, First Department of Pediatrics, Semmelweis University, Budapest, Hungary.

出版信息

J Craniofac Surg. 2017 Nov;28(8):1950-1954. doi: 10.1097/SCS.0000000000003995.

Abstract

BACKGROUND

In cleft palate surgery, there is currently no consensus on the management of patients with Pierre Robin Sequence (PRS). The authors aimed to evaluate the treatment strategy of cleft palate in our centers, with emphasis on patients with PRS, as the authors noted some patients with severe respiratory distress. Moreover, the authors aimed to investigate the prevalence of postoperative respiratory complications, using a modified-Furlow palatoplasty in combination with intravelar veloplasty in both patients with PRS and patients with non-PRS.

METHODS

The authors retrospectively identified all consecutive patients, both PRS and non-PRS, who underwent palate repair between January 1, 2012 and December 15, 2014 at 2 cooperating cleft centers (Bruges, Belgium; Budapest, Hungary). The treatment modality was uniform and performed by the same 2 surgeons.

RESULTS

In 92 consecutive patients, 4 patients experienced respiratory distress after palate repair. The female-to-male ratio was 1:1. The mean age at surgery in these 4 patients was 15 months (range 13-19 months). Fifteen percent (2/13) of patients with PRS experienced respiratory distress in comparison to 3% (2/79) of non-PRS (χ = 4.43; P = 0.035).

CONCLUSIONS

This is the first report of postoperative respiratory difficulties, while using a modified-Furlow palatoplasty in combination with intravelar veloplasty. In the present author's experience, the authors suggest to perform a 2-stage closure of the cleft palate in patients with PRS and to do so at a later age, when the palatal tissues and airway structures are more mature. Moreover, patients with PRS should be monitored closely, as they can present with different degrees of respiratory distress after palatoplasty.

摘要

背景

在腭裂手术中,目前对于Pierre Robin序列征(PRS)患者的治疗尚无共识。作者旨在评估我们中心腭裂的治疗策略,重点关注PRS患者,因为作者注意到一些患者存在严重的呼吸窘迫。此外,作者旨在研究采用改良Furlow腭成形术联合腭内肌成形术治疗PRS患者和非PRS患者术后呼吸并发症的发生率。

方法

作者回顾性确定了2012年1月1日至2014年12月15日期间在2个合作腭裂中心(比利时布鲁日;匈牙利布达佩斯)接受腭裂修复术的所有连续患者,包括PRS患者和非PRS患者。治疗方式统一,由同2位外科医生进行操作。

结果

在92例连续患者中,4例患者在腭裂修复术后出现呼吸窘迫。男女比例为1:1。这4例患者的平均手术年龄为15个月(范围13 - 19个月)。PRS患者中有15%(2/13)出现呼吸窘迫,而非PRS患者中这一比例为3%(2/79)(χ² = 4.43;P = 0.035)。

结论

这是关于使用改良Furlow腭成形术联合腭内肌成形术术后出现呼吸困难的首份报告。根据作者的经验,建议对PRS患者分两阶段关闭腭裂,并在腭部组织和气道结构更成熟的较晚年龄进行。此外,应对PRS患者进行密切监测,因为他们在腭裂修复术后可能会出现不同程度的呼吸窘迫。

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