Butcher A, Richards T
Division of Surgery and Interventional Science, University College London, London, UK.
Transfus Med. 2018 Apr;28(2):150-157. doi: 10.1111/tme.12476. Epub 2017 Sep 22.
Pre-operative anaemia and perioperative red blood cell transfusion carry significant consequence when it comes to surgical outcomes. The establishment of patient-centred clinical pathways has been designed to harness and endorse good transfusion practice, termed the three pillars of patient blood management (PBM). These focus on the timely and appropriate management of anaemia, prevention of blood loss and restrictive transfusion where appropriate. This article reviews the current evidence and ongoing research in the field of PBM in surgery. Strategies to implement PBM have shown significant benefits in appropriate transfusion practice, reduced costs and improved length of hospital stay. Recently published national quality standards have recognised the features of the PBM blueprint such as the consideration of alternatives to red blood cell transfusion, the active measures to reduce perioperative blood loss and the appropriate management of post-operative anaemia. Adopting PBM in surgical patients should be paramount to reduce the risks posed by perioperative anaemia and blood transfusions. The principles of PBM help structure the interventions and decisions relating to anaemia and blood transfusion, but, more importantly, represent a paradigm shift towards a more considered approach to blood transfusion, acknowledging its risks, preventatives and alternatives.
术前贫血和围手术期红细胞输血对手术结果有着重大影响。以患者为中心的临床路径的建立旨在利用并支持良好的输血实践,即所谓的患者血液管理(PBM)的三大支柱。这些支柱侧重于贫血的及时和适当管理、失血的预防以及在适当情况下的限制性输血。本文综述了外科手术中PBM领域的现有证据和正在进行的研究。实施PBM的策略已在适当的输血实践、降低成本和缩短住院时间方面显示出显著益处。最近发布的国家质量标准认可了PBM蓝图的特点,如考虑红细胞输血的替代方法、减少围手术期失血的积极措施以及术后贫血的适当管理。在手术患者中采用PBM对于降低围手术期贫血和输血带来的风险至关重要。PBM的原则有助于构建与贫血和输血相关的干预措施和决策,但更重要的是,它代表了一种范式转变,即朝着更审慎的输血方法转变,承认输血的风险、预防措施和替代方法。