Respiration driven C1- uptake by submitochondrial particles.

Both Mg2+ and oligomycin are required for the establishment of a membrane potential and the uptake of Cl- in submitochondrial particles prepared from rat liver. The effect of oligomycin is considered to be due to blocking of H+ conduction through exposed F0 channels of the ATPase complex whereas Mg2+ may more directly affect the anion-conducting channel.