Li Yue, Hu Zhongzhou, Wang Jianchang, Zhang Yue, Chen Zhong, Zhang Hongchao
Department of Cardiac Surgery, Air Force General Hospital of People's Liberation Army, Beijing, China.
Department of Vascular Surgery, The Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China.
Ann Vasc Surg. 2018 Feb;47:305-315. doi: 10.1016/j.avsg.2017.09.006. Epub 2017 Sep 22.
Endovascular chimney technique has been increasingly reported in treating aortic arch pathologies. However, there are still concerns about this technique. The aim of this study is to evaluate the safety and outcome of this technique by performing a systematic review and meta-analysis.
Medline, EMBASE, and Cochrane databases were systematically searched to identify studies on the management of aortic arch pathologies using chimney technique. Studies were reviewed and selected using a priori defined criteria by 2 independent observers who abstracted data on study characteristics, study quality, and outcomes. The extracted data were presented as rate and were converted through arcsine transformations. Individual studies were evaluated and analyzed for 5 ending factors such as technical success, 30-day mortality, patency, perioperative endoleak, and stroke. Heterogeneity of the studies was determined using the chi-square distribution-based Q test and quantified by I statistics. The meta-analyses were performed using both random effects model and fixed-effect model.
Twelve studies with a total of 379 patients met the inclusion criteria. The pooled technical success rate of chimney technique was 91% (95% confidence interval [CI]: 87-94%). After patients were treated with chimney technique, the rate of 30-day mortality was 4% (95% CI: 2-7%), the rate of patency was 93% (95% CI: 89-96%), the rate of perioperative endoleak was 21% (95% CI: 17-26%), and the rate of stroke was 5% (95% CI: 3-8%).
This study indicates that using chimney technique for treating aortic arch pathologies produced satisfied midterm outcomes in both elective and emergent situations.
血管腔内烟囱技术治疗主动脉弓病变的报道日益增多。然而,该技术仍存在一些问题。本研究旨在通过系统评价和荟萃分析评估该技术的安全性和疗效。
系统检索Medline、EMBASE和Cochrane数据库,以确定使用烟囱技术治疗主动脉弓病变的研究。由2名独立观察者根据预先定义的标准对研究进行审查和筛选,提取有关研究特征、研究质量和结果的数据。提取的数据以率的形式呈现,并通过反正弦变换进行转换。对5个结局因素进行个体研究评估和分析,包括技术成功率、30天死亡率、通畅率、围手术期内漏和卒中。使用基于卡方分布的Q检验确定研究的异质性,并通过I统计量进行量化。荟萃分析采用随机效应模型和固定效应模型。
12项研究共379例患者符合纳入标准。烟囱技术的综合技术成功率为91%(95%置信区间[CI]:87-94%)。患者接受烟囱技术治疗后,30天死亡率为4%(95%CI:2-7%),通畅率为93%(95%CI:89-96%),围手术期内漏率为21%(95%CI:17-26%),卒中率为5%(95%CI:3-8%)。
本研究表明,在择期和急诊情况下,使用烟囱技术治疗主动脉弓病变均可获得满意的中期疗效。