Yoshimura Satoshi, Kawano Hiroaki, Minami Takako, Tsuneto Akira, Nakata Tomoo, Koga Seiji, Ikeda Satoshi, Hayashi Tomayoshi, Maemura Koji
Department of Cardiology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Department of Pathology, Shimabara Prefectural Hospital, Japan.
Intern Med. 2017 Nov 15;56(22):3057-3060. doi: 10.2169/internalmedicine.9057-17. Epub 2017 Sep 25.
Calcified amorphous tumor (CAT) is a rare, non-neoplastic tumor involving calcium deposition in amorphous materials. Although its etiology is unknown, cases have frequently been reported in patients with hemodialysis for chronic kidney disease. We herein describe a case of cardiac CAT in a 64-year-old woman who had been on hemodialysis for diabetic nephropathy for 20 years, and the findings of the present patient, in association with the findings of previous case reports, suggest that end-stage renal disease seems to play an important role in the onset of CAT, especially in CAT formation at the mitral annulus, which appears to differ from CAT occurring at other sites.
钙化性无定形肿瘤(CAT)是一种罕见的非肿瘤性肿瘤,其特征为钙在无定形物质中沉积。尽管其病因不明,但在慢性肾病血液透析患者中经常有病例报道。我们在此描述一例64岁女性的心脏CAT病例,该患者因糖尿病肾病接受血液透析20年。结合既往病例报告的结果,本病例患者的发现提示终末期肾病似乎在CAT的发病中起重要作用,尤其是在二尖瓣环处的CAT形成,这似乎与其他部位发生的CAT有所不同。