心脏钙化性非典型肿瘤与多发性骨髓瘤相关。
Cardiac calcified amorphous tumour associated with multiple myeloma.
机构信息
Tokyo Teishin Hospital, Chiyoda-ku, Japan
Tokyo Teishin Hospital, Chiyoda-ku, Japan.
出版信息
BMJ Case Rep. 2020 Apr 28;13(4):e233679. doi: 10.1136/bcr-2019-233679.
Abstract
We report an 86-year-old woman who was diagnosed with multiple myeloma (MM) and was receiving chemotherapy since the age of 82. A high echoic mass attached to the mitral valve was observed on transthoracic echocardiography 4 years after the treatment. The possibility of malignancy could not be ruled out, and hence, the mass was excised surgically. Pathologically, most of the mass consisted of calcified lesion without tumour tissue, and these findings were not inconsistent with calcified amorphous tumour (CAT). This case suggests that CAT may be associated with MM and has been reported after a thorough literature review.
摘要
我们报告了一例 86 岁女性，她在 82 岁时被诊断患有多发性骨髓瘤（MM）并接受化疗。在治疗后 4 年，经胸超声心动图检查发现附着在二尖瓣上的高回声肿块。不能排除恶性肿瘤的可能性，因此手术切除了肿块。病理上，大部分肿块由钙化病变组成，没有肿瘤组织，这些发现与钙化不定形肿瘤（CAT）相符。本病例提示 CAT 可能与 MM 有关，并在彻底的文献复习后报道。
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本文引用的文献
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Lancet Oncol. 2019 Oct;20(10):e566-e581. doi: 10.1016/S1470-2045(19)30336-5. Epub 2019 Sep 3.
2
A case of cardiac calcified amorphous tumor (cardiac CAT) causing acute embolism in right common iliac artery.一例导致右髂总动脉急性栓塞的心脏钙化性无定形肿瘤（心脏CAT）。
J Cardiol Cases. 2014 Dec 12;11(3):81-84. doi: 10.1016/j.jccase.2014.10.012. eCollection 2015 Mar.
3
[Multiple Myeloma: from Diagnosis to the Up-to-date Treatment. Topics: III. Bone Disease in Multiple Myeloma].[多发性骨髓瘤：从诊断到最新治疗。主题：III. 多发性骨髓瘤中的骨病]
Nihon Naika Gakkai Zasshi. 2016 Jul;105(7):1216-23.
4
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Intern Med. 2017 Nov 15;56(22):3057-3060. doi: 10.2169/internalmedicine.9057-17. Epub 2017 Sep 25.
5
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6
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7
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