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番荔枝种子诱发的角膜炎:印度南部一种有害的传统习俗。

Custard apple seed induced keratitis: a harmful traditional practice in South India.

作者信息

Devi Nivean Pratheeba, Malarkodi S, Nishanth M, Nivean M

机构信息

M.N. Eye Hospital, Chennai, India.

出版信息

GMS Ophthalmol Cases. 2017 Sep 1;7:Doc23. doi: 10.3205/oc000074. eCollection 2017.

DOI:10.3205/oc000074
PMID:28944154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5598200/
Abstract

Custard apple seeds have been used as a traditional remedy for scalp infestation of lice and dandruff since many years in our part of the world. Not many people, doctors even, are aware about the ill effects of this practice. Surprisingly, there are very few reports on poisoning due to these seeds and the management is not very well streamlined. Rohit Shetty et al. highlighted the ill effects of the seeds and the need to avoid steroids in these cases as they worsen the clinical scenario. We present 2 patients who developed keratoconjunctivitis due to ocular exposure with custard apple seeds. However, we managed our cases slightly differently. We scraped off the loose epithelium and patched the eye for a day or two with topical antibiotics and lubricants. The patients responded very well. We highlight our series to describe an alternate way of treatment for cases with custard apple seed injury.

摘要

在我们这个地区,番荔枝种子多年来一直被用作治疗头皮虱虫感染和头皮屑的传统药物。即使是医生,也没有多少人意识到这种做法的不良影响。令人惊讶的是,关于这些种子中毒的报道非常少,而且治疗管理也没有很好地规范。罗希特·谢蒂等人强调了这些种子的不良影响以及在这些病例中避免使用类固醇的必要性,因为类固醇会使临床情况恶化。我们报告了2例因眼部接触番荔枝种子而发生角膜结膜炎的患者。然而,我们对病例的处理略有不同。我们刮除了疏松的上皮组织,并用局部抗生素和润滑剂对眼睛进行了一两天的包扎。患者反应良好。我们通过这个病例系列来描述番荔枝种子损伤病例的另一种治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/f723db340239/OC-07-23-g-006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/d3a3e52a888c/OC-07-23-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/9ee3069ab95b/OC-07-23-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/eb704eed681e/OC-07-23-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/eb6796036bb6/OC-07-23-g-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/02e5788d20ee/OC-07-23-g-005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/f723db340239/OC-07-23-g-006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/d3a3e52a888c/OC-07-23-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/9ee3069ab95b/OC-07-23-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/eb704eed681e/OC-07-23-g-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/eb6796036bb6/OC-07-23-g-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/02e5788d20ee/OC-07-23-g-005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728a/5598200/f723db340239/OC-07-23-g-006.jpg

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本文引用的文献

1
Ocular toxicity by seeds of Annona squamosa (custard apple).番荔枝(释迦果)种子引起的眼毒性。
Indian J Ophthalmol. 2016 Aug;64(8):611-3. doi: 10.4103/0301-4738.191514.
2
Six cytotoxic annonaceous acetogenins from Annona squamosa seeds.从番荔枝种子中分离得到的 6 种细胞毒性角鲨烯型乙酰氧基化合物。
Food Chem. 2012 Dec 1;135(3):960-6. doi: 10.1016/j.foodchem.2012.05.041. Epub 2012 May 17.
3
Pathogenesis, clinical features and management of recurrent corneal erosions.复发性角膜糜烂的发病机制、临床特征及治疗
Eye (Lond). 2006 Jun;20(6):635-44. doi: 10.1038/sj.eye.6702005. Epub 2005 Jul 15.