State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, PR China.
State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, PR China.
Bioresour Technol. 2018 Jan;247:116-124. doi: 10.1016/j.biortech.2017.09.043. Epub 2017 Sep 8.
Although AHL-mediated quorum sensing (QS) signaling has been proved to be ecologically important in biofilm formation and aerobic granulation process, the biological role of AHL in anaerobic granule has not been experimentally investigated. In this paper, we explored the AHL level in 10 full-scale industrial anaerobic granular bioreactors and detected a total of 4 kinds of AHLs. C8-HSL and C10-HSL were indicated to be the potentially universal QS signal molecules in anaerobic granules and involved in extracellular polymeric substance (EPS) production and granulation process. The add-back experiments further supported the hypothesis that C8-HSL and C10-HSL might play an important role in facilitating anaerobic granulation through regulation of EPS synthesis. 12 Microorganisms might be regulated by AHL to play an important role in EPS production. This study provides a foundation for exploring the function of AHL in anaerobic granular systems, which may shed light on advanced AHL-based anaerobic granulation strategy.
尽管 AHL 介导的群体感应 (QS) 信号已被证明在生物膜形成和好氧颗粒化过程中具有重要的生态意义，但 AHL 在厌氧颗粒中的生物学作用尚未通过实验进行研究。本文中，我们探究了 10 个全规模工业厌氧颗粒生物反应器中的 AHL 水平，共检测到 4 种 AHL。C8-HSL 和 C10-HSL 被认为是厌氧颗粒中潜在的通用 QS 信号分子，参与胞外聚合物 (EPS) 的产生和颗粒化过程。添加回补实验进一步支持了假说，即 C8-HSL 和 C10-HSL 可能通过调节 EPS 合成在促进厌氧颗粒化方面发挥重要作用。12 种微生物可能受到 AHL 的调节，在 EPS 产生中发挥重要作用。本研究为探索 AHL 在厌氧颗粒系统中的功能提供了基础，这可能为基于 AHL 的先进厌氧颗粒化策略提供启示。
Zotero 插件