1Department of Neurosurgery, Kindai University Faculty of Medicine, Osaka; and.
2Department of Neurosurgery, Nara Hospital, Kindai University Faculty of Medicine, Nara, Japan.
J Neurosurg. 2018 Aug;129(2):465-470. doi: 10.3171/2017.3.JNS162563. Epub 2017 Sep 15.
OBJECTIVE The vascular lumen of an acutely occluded internal carotid artery (ICA) generally contains numerous thrombi. Therefore, carotid angiography on the affected side during revascularization therapy of acute ICA occlusion has a potential risk of causing distal embolization. In this study the authors propose the use of contralateral carotid angiography. METHODS Six patients with acute ICA occlusion underwent revascularization therapy using a stent retriever or Penumbra system. Revascularization therapy was performed with placement of a 9-Fr balloon-guiding catheter (BGC) in the affected ICA and a 4-Fr diagnostic catheter in the contralateral ICA. During the procedure, the 9-Fr BGC was kept inflated, and all control angiography was performed from the 4-Fr diagnostic catheter. After thrombectomy, contralateral carotid angiography combined with manual aspiration from the 9-Fr BGC was performed to assess the presence or absence of residual thrombi in the affected ICA. The 9-Fr BGC was deflated only after the complete absence of residual thrombi in the affected ICA was confirmed. RESULTS The time required for introducing the 4-Fr diagnostic catheter into the contralateral ICA was within a few minutes in all patients. Residual thrombi in the affected ICA were found in 3 of 6 patients. The residual thrombi in these 3 patients were completely removed; thus, distal embolization was prevented. CONCLUSIONS Contralateral carotid angiography is useful for avoiding distal embolization during revascularization therapy of acute ICA occlusion. Further studies involving a larger number of patients are warranted to verify the clinical efficacy of this contralateral carotid angiography.
急性颈内动脉闭塞(ICA)的血管管腔通常含有大量血栓。因此,在急性 ICA 闭塞的再通治疗期间,对受累侧进行颈动脉造影具有引起远端栓塞的潜在风险。在本研究中,作者提出使用对侧颈动脉造影。
6 例急性 ICA 闭塞患者接受支架取栓术或 Penumbra 系统治疗。通过在受累 ICA 中放置 9Fr 球囊引导导管(BGC)和在对侧 ICA 中放置 4Fr 诊断导管来进行再通治疗。在该过程中,保持 9Fr BGC 充气,所有控制性血管造影均通过 4Fr 诊断导管进行。在血栓切除术之后,进行对侧颈动脉造影并通过 9Fr BGC 进行手动抽吸,以评估受累 ICA 中是否存在残余血栓。仅在确认受累 ICA 中不存在残余血栓后,才将 9Fr BGC 放气。
所有患者将 4Fr 诊断导管引入对侧 ICA 的时间均在几分钟内。6 例患者中有 3 例发现受累 ICA 中有残余血栓。这 3 例患者的残余血栓均被完全清除,从而防止了远端栓塞。
对侧颈动脉造影在急性 ICA 闭塞的再通治疗中可避免远端栓塞。需要进一步进行更多患者的研究以验证这种对侧颈动脉造影的临床疗效。