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挪威中部胃肠外科、内科和老年病房入院时药物史的差异:一项横断面研究。

Discrepancies in drug histories at admission to gastrointestinal surgery, internal medicine and geriatric hospital wards in Central Norway: a cross-sectional study.

机构信息

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Clinical Pharmacy Services, Central Norway Hospital Pharmacy Trust, Trondheim, Norway.

出版信息

BMJ Open. 2017 Sep 24;7(9):e013427. doi: 10.1136/bmjopen-2016-013427.

Abstract

OBJECTIVES

To compare discrepancies in drug histories among patients acutely admitted to different hospital wards, classify the discrepancies according to their potential clinical impact and identify appropriate selection criteria for patients that should be subject to a detailed drug history at admission.

DESIGN

Cross-sectional study.

SETTING

Two gastrointestinal surgery wards and one geriatric ward at St Olav's University Hospital in Trondheim and two general internal medicine wards at Ålesund Hospital in Ålesund, Norway.

PARTICIPANTS

All patients acutely admitted to these wards during a period of three months were asked to participate in the study. A total of 168 patients were included. For each patient, drug information available at admission was compared with information from drug lists obtained from the general practitioner and (if applicable) the home care services/the nursing home.

PRIMARY AND SECONDARY OUTCOME MEASURES

Number of patients with one or more discrepancies in their drug history. Type and clinical impact of the discrepancies found. Selection criteria for patients that should be subject to a detailed drug history.

RESULTS

In total, 83% had at least one discrepancy in their drug history. Omission of a drug accounted for 72% of the discrepancies, whereas a difference in dosing was the cause of the remaining 28%. 9% of the discrepancies had the potential to cause severe harm or discomfort. We found no significant differences in the number of discrepancies between hospital wards, genders, ages or levels of care.

CONCLUSIONS

This study demonstrates the importance of collecting drug information from all available sources when a patient is admitted to hospital. As we found no significant differences in discrepancies between subgroups of patients, we suggest that medication reconciliation should be performed for all patients.

摘要

目的

比较不同医院病房急性入院患者的药物史差异,根据其潜在的临床影响对差异进行分类,并确定应在入院时详细了解药物史的患者的适当选择标准。

设计

横断面研究。

地点

挪威特隆赫姆圣奥拉夫大学医院的两个胃肠外科病房和一个老年病房,以及奥勒松医院的两个普通内科病房。

参与者

在三个月期间,邀请这些病房内所有急性入院的患者参与研究。共纳入 168 名患者。对于每一位患者,入院时的药物信息与从全科医生处获得的药物清单以及(如有)家庭护理服务/养老院获得的信息进行比较。

主要和次要结果

药物史有一个或多个差异的患者人数。发现的差异的类型和临床影响。应进行详细药物史评估的患者的选择标准。

结果

共有 83%的患者药物史至少有一处差异。药物遗漏占差异的 72%,而剂量差异则占剩余的 28%。9%的差异有可能造成严重伤害或不适。我们没有发现病房、性别、年龄或护理水平之间差异数量的显著差异。

结论

本研究表明,当患者入院时,从所有可用来源收集药物信息非常重要。由于我们在患者亚组之间的差异没有发现显著差异,因此我们建议应所有患者进行药物重整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d99a/5623371/6d9c2cb00410/bmjopen-2016-013427f01.jpg

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