Shah Meera, Hurt Ryan T, Mundi Manpreet S
Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.
Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Curr Gastroenterol Rep. 2017 Sep 25;19(11):55. doi: 10.1007/s11894-017-0598-1.
The worldwide prevalence of obesity is increasing. Obesity is strongly associated with many chronic health conditions that have been shown to improve with weight loss. However, counseling patients on weight loss can be challenging. Identifying specific aspects of weight management may personalize the conversation about weight loss and better address the individual patient's health goals and perceived barriers to change.
Physical and behavioral phenotypes are being identified to better tailor treatment recommendations, given lack of efficacy of currently available interventions. The current review provides a summary of the evidence behind the management of several recognized clinical phenotypes, to include body fat distribution (e.g., central obesity), muscle mass (e.g., sarcopenic obesity of the elderly), and problematic eating behaviors (e.g., cravings). Identifying specific aspects of weight management may personalize the conversation about weight loss and better address the individual patient's health goals and perceived barriers to change.
全球肥胖患病率正在上升。肥胖与许多慢性健康状况密切相关,而这些状况已被证明会随着体重减轻而改善。然而,为患者提供减肥咨询可能具有挑战性。确定体重管理的具体方面可以使关于减肥的谈话个性化,并更好地实现个体患者的健康目标以及应对其感知到的改变障碍。
鉴于目前可用干预措施缺乏疗效,正在确定身体和行为表型,以更好地调整治疗建议。本综述总结了几种公认临床表型管理背后的证据,包括体脂分布(如中心性肥胖)、肌肉量(如老年人的肌少症肥胖)和问题饮食行为(如渴望)。确定体重管理的具体方面可以使关于减肥的谈话个性化,并更好地实现个体患者的健康目标以及应对其感知到的改变障碍。