Pozdniakov O M, Nikulin V G
Biull Eksp Biol Med. 1988 Mar;105(3):359-62.
Neuromuscular junctions in the diaphragm muscle of rats were studied, using a usual chemical fixation technique and quick prefreezing of the muscle. The number of synaptic vesicles in the vicinity of presynaptic membrane decreased significantly during synaptic function activation. Quantitative investigation of axon terminal vesicle apparatus revealed heterogeneity in the size of synaptic vesicle pool. The pattern of synaptic vesicle size distribution in different functional states of the synapse suggests that size heterogeneity reflects their functional peculiarities.
采用常规化学固定技术和肌肉快速预冷冻的方法，对大鼠膈肌中的神经肌肉接头进行了研究。在突触功能激活过程中，突触前膜附近的突触小泡数量显著减少。对轴突终末小泡装置的定量研究揭示了突触小泡池大小的异质性。突触在不同功能状态下突触小泡大小分布模式表明，大小异质性反映了它们的功能特性。
