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[汉坦病毒在捷克共和国引发致命性出血热]

[Hantavirus causing fatal haemorrhagic fever in the Czech Republic].

作者信息

Zelená H, Rumlerová M, Kodras K, Beroušková P, Mrázek J, Smetana J

出版信息

Epidemiol Mikrobiol Imunol. 2017 Fall;66(3):149-152.

Abstract

Hantaviruses are RNA viruses of the family Bunyaviridae. Their hosts are mammals of the orders rodents (voles, rats, mice), insectivores (shrews, moles), and chiroptera (bats). Hantaviruses are present in many areas of Europe, the Americas, Asia, and Africa. In the Czech Republic, the occurrence of five species of hantaviruses has been reported (Dobrava/Belgrade, Puumala, Tula, Seewis, and Asikkala), with the first three of them causing human diseases. Although the course of hantavirus infections can be very serious, there is a low awareness of these diseases, even among health professionals, and hantavirus is often not considered in the diagnosis. A case history is reported of a patient who developed hantavirus haemorrhagic fever with renal syndrome (HFRS) with fatal outcome. The patient presented with typical clinical signs, but the correct diagnosis was only made at post mortem.

摘要

汉坦病毒是布尼亚病毒科的RNA病毒。其宿主为啮齿目(田鼠、大鼠、小鼠)、食虫目(鼩鼱、鼹鼠)和翼手目(蝙蝠)的哺乳动物。汉坦病毒存在于欧洲、美洲、亚洲和非洲的许多地区。在捷克共和国,已报告有五种汉坦病毒(多布拉伐/贝尔格莱德病毒、普马拉病毒、图拉病毒、塞维斯病毒和阿西卡拉病毒)出现,其中前三种可导致人类疾病。尽管汉坦病毒感染的病程可能非常严重,但即使在卫生专业人员中,对这些疾病的认识也很低,而且在诊断时往往不考虑汉坦病毒。本文报告了一例患汉坦病毒肾综合征出血热(HFRS)并导致死亡的患者的病例史。该患者表现出典型的临床症状,但直到死后才做出正确诊断。

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