1 Department of Emergency Medicine, Medical University of Vienna, Austria.
2 Ludwig Boltzman Institute, Cluster for Cardiovascular Research, Austria.
Eur Heart J Acute Cardiovasc Care. 2018 Aug;7(5):423-431. doi: 10.1177/2048872617731894. Epub 2017 Sep 26.
While guidelines mentioned supraglottic airway management in the case of out-of- hospital cardiac arrest, robust data of their impact on the patient outcome remain scare and results are inconclusive.
To assess the impact of the airway strategy on the patient outcome we prospectively enrolled 2224 individuals suffering cardiac arrest who were treated by the Viennese municipal emergency medical service. To control for potential confounders, propensity score matching was performed. Patients were matched in four groups with a 1:1:1:1 ratio ( n=210/group) according to bag-mask-valve, laryngeal tube, endotracheal intubation and secondary endotracheal intubation after primary laryngeal tube ventilation.
The laryngeal tube subgroup showed the lowest 30-day survival rate among all tested devices ( p<0.001). However, in the case of endotracheal intubation after primary laryngeal tube ventilation, survival rates were comparable to the primary endotracheal tube subgroup. The use of a laryngeal tube was independently and directly associated with mortality with an adjusted odds ratio of 1.97 (confidence interval: 1.14-3.39; p=0.015). Additionally, patients receiving laryngeal tube ventilation showed the lowest rate of good neurological performance (6.7%; p<0.001) among subgroups. However, if patients received endotracheal intubation after initial laryngeal tube ventilation, the outcome proved to be significantly better (9.5%; p<0.001).
We found that the use of a laryngeal tube for airway management in cardiac arrest was significantly associated with poor 30-day survival rates and unfavourable neurological outcome. A primary endotracheal airway management needs to be considered at the scene, or an earliest possible secondary endotracheal intubation during both pre-hospital and in-hospital post-return of spontaneous circulation critical care seems crucial and most beneficial for the patient outcome.
尽管指南中提到了在院外心脏骤停的情况下进行声门上气道管理,但关于其对患者预后影响的有力数据仍然很少,结果也不确定。
为了评估气道策略对患者预后的影响,我们前瞻性纳入了 2224 名接受维也纳市紧急医疗服务治疗的心脏骤停患者。为了控制潜在的混杂因素,进行了倾向评分匹配。根据球囊面罩、喉管、气管插管和初次喉管通气后再次气管插管,将患者以 1:1:1:1 的比例(每组 210 例)分为 4 组进行匹配。
在所有测试设备中,喉管组的 30 天生存率最低(p<0.001)。然而,在初次喉管通气后进行气管插管的情况下,生存率与初次气管插管组相当。初次使用喉管与死亡率独立且直接相关,校正比值比为 1.97(置信区间:1.14-3.39;p=0.015)。此外,在亚组中,接受喉管通气的患者神经功能良好的比例最低(6.7%;p<0.001)。然而,如果患者在初次喉管通气后接受气管插管,结果则显著更好(9.5%;p<0.001)。
我们发现,在心脏骤停患者中使用喉管进行气道管理与 30 天生存率低和不良神经结局显著相关。在现场需要考虑进行气管内气道管理,或在院前和自主循环恢复后的院内关键护理期间尽早进行二次气管插管,这对患者预后似乎至关重要,也最有益。