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评估心肺复苏期间接受机械通气的院外心脏骤停患者的通气和灌注标志物。

An assessment of ventilation and perfusion markers in out-of-hospital cardiac arrest patients receiving mechanical CPR with endotracheal or supraglottic airways.

机构信息

Department of Emergency Medicine, University of Florida, PO Box 100186, Gainesville, FL 32610, USA.

University of Pittsburgh School of Medicine, 3550 Terrace St, Pittsburgh, PA 15213, USA.

出版信息

Resuscitation. 2018 Jan;122:61-64. doi: 10.1016/j.resuscitation.2017.11.054. Epub 2017 Nov 23.

Abstract

AIM OF THE STUDY

Mechanical chest compression (MCPR) devices are considered equivalent to manual compressions in patient outcomes in out-of-hospital cardiac arrest (OHCA). However, recent data suggest possible harm in patients with a supraglottic airway device (SGA) during MCPR. The aim of this study was to evaluate differences in direct and indirect markers of ventilation and perfusion in patients with cardiac arrest receiving MCPR and who had their airway managed with an endotracheal tube (ETT) or SGA.

METHODS

We retrospectively reviewed Emergency Medical Services (EMS) agencies and emergency department (ED) records over a two-year period. We included patients with OHCA who underwent MCPR and who had an advanced airway placed. The primary outcome was differences in intra-arrest end-tidal carbon dioxide (etCO2) measurements. Secondary outcomes included intra-arrest ventilation rates, rates of prehospital return of spontaneous circulation (ROSC), blood pressure upon prehospital ROSC, and 24-h survival.

RESULTS

Valid data sets were available for 126 patients. Eighty-four (66.7%) had an ETT placed, and 42 (33.3%) had a SGA placed. Twenty-eight (22.6%) achieved prehospital ROSC. Twenty-four-hour survival data were available for 13 (10.3%) of these patients. There were no significant differences in primary or secondary outcomes.

CONCLUSION

In this retrospective study, we found no evidence of differences in markers of ventilation, perfusion or prehospital ROSC and survival in patients with OHCA who had their airway managed with either an ETT or SGA while receiving MCPR.

摘要

研究目的

机械胸部按压(MCPR)设备在院外心脏骤停(OHCA)患者的预后中被认为等同于手动按压。然而,最近的数据表明,在接受 MCPR 的患者中,使用声门上气道装置(SGA)时可能会造成伤害。本研究旨在评估在接受 MCPR 且气道管理使用气管内管(ETT)或 SGA 的心脏骤停患者中,直接和间接通气和灌注标志物的差异。

方法

我们回顾性地审查了为期两年的紧急医疗服务(EMS)机构和急诊部(ED)的记录。我们纳入了接受 MCPR 且放置了高级气道的 OHCA 患者。主要结局是在心脏骤停期间测量的呼气末二氧化碳(etCO2)差异。次要结局包括心脏骤停期间的通气率、院前自主循环恢复(ROSC)的发生率、院前 ROSC 时的血压以及 24 小时生存率。

结果

有 126 名患者的有效数据集。84 名(66.7%)患者放置了 ETT,42 名(33.3%)患者放置了 SGA。28 名(22.6%)患者实现了院前 ROSC。其中 13 名(10.3%)患者的 24 小时生存数据可用。主要或次要结局均无显著差异。

结论

在这项回顾性研究中,我们没有发现证据表明在接受 MCPR 且气道管理使用 ETT 或 SGA 的 OHCA 患者中,通气、灌注或院前 ROSC 和生存率的标志物存在差异。

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