a University Medical Unit, National Hospital Colombo , Colombo , Sri Lanka.
b Faculty of Medicine, Department of Clinical Medicine , University of Colombo , Colombo , Sri Lanka.
Pathog Glob Health. 2017 Oct;111(7):333-342. doi: 10.1080/20477724.2017.1370528. Epub 2017 Sep 26.
Toxoplasmosis is an infection caused by the intracellular protozoan parasite Toxoplasma gondii, and is associated with clinically significant infection in immunocompromised individuals. Vertical transmission during pregnancy can manifest as congenital toxoplasmosis in the neonate, and can have serious consequences. This review aims to describe the modalities for prophylaxis of toxoplasmosis in susceptible populations, and focuses on the following: (1) prophylaxis of congenital toxoplasmosis; (2) prophylaxis of toxoplasmosis in patients with HIV/AIDS; and (3) prophylaxis of toxoplasmosis in transplant recipients.
弓形虫病是一种由细胞内原虫寄生虫弓形虫引起的感染,与免疫功能低下个体的临床显著感染有关。怀孕期间的垂直传播可在新生儿中表现为先天性弓形虫病,并可能产生严重后果。本综述旨在描述易感人群中弓形虫病的预防方法,并重点介绍以下内容:(1)先天性弓形虫病的预防;(2)HIV/AIDS 患者的弓形虫病预防;(3)移植受者的弓形虫病预防。