Fraga Rafael Cavanellas, Kakizaki Priscila, Valente Neusa Yuriko Sakai, Portocarrero Larissa Karine Leite, Teixeira Mônica Fernandes Senise, Senise Priscilla Fernandes
Private clinic - Vitória (ES), Brazil.
Dermatology unit, Hospital do Servidor Público Estadual de São Paulo - São Paulo (SP), Brazil.
An Bras Dermatol. 2017 Jul-Aug;92(4):571-572. doi: 10.1590/abd1806-4841.20175211.
Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases.
黑尔福特-瓦尔登斯特伦综合征是结节病的一种罕见亚急性变体,其特征为腮腺或唾液腺肿大、面神经麻痹和前葡萄膜炎。在受影响器官的解剖病理学中发现有外周淋巴细胞缺乏的肉芽肿。它通常是自限性的,在12至36个月内可治愈,但也有一些病程延长的病例报道。该综合征的诊断基于临床症状,治疗取决于全身损害的程度。口服糖皮质激素是一线治疗选择。死亡率在病例的1%至5%之间。