Kinoshita Hiroyuki, Akahori Takahiko, Nakamura Emi, Okawa Hazuki, Kawahito Shinji, Kitahata Hiroshi, Fujiwara Yoshihiro
Department of Anesthesiology, Aichi Medical University School of Medicine.
Departments of Anesthesiology, Tokushima University Hospital.
J Med Invest. 2017;64(3.4):228-232. doi: 10.2152/jmi.64.228.
Whether the near-infrared spectroscopy (NIRS) technology correctly detects the changes in oxygenation related to ischemia and reperfusion of organs and tissues other than brain remains unclear. The present study examined how different tissue oxygenation parameters derived from NIRS reflect the changes in the forearm blood flow (FBF) according to the brief ischemia and the subsequent reperfusion, and whether values of these parameters move in parallel with the medial and lateral sides of FBF. Thirteen volunteers underwent the prospective observational study. The tissue oxygenation index (TOI), regional saturation of oxygen (rSO), skin tissue oxygenation (StO), and FBF values were evaluated in the forearm. Medial rSO values at 1 to 3 minutes after the termination of brief ischemia were higher than lateral rSO and respective TOI values. FBF and StO values quickly increased according to the cessation of brief ischemia, whereas the medial and lateral values did not differ during and after the brief ischemia. TOI and StO, but not rSO, reflected changes in FBF of both medial and lateral sides simultaneously in response to the reperfusion after brief ischemia. The muscle tissue oxygenation during reperfusion favors the use of TOI and StO, but not rSO, as the surrogate parameter. J. Med. Invest. 64: 228-232, August, 2017.
近红外光谱（NIRS）技术能否正确检测除脑以外的器官和组织缺血及再灌注相关的氧合变化尚不清楚。本研究探讨了从NIRS得出的不同组织氧合参数如何根据短暂缺血及随后的再灌注反映前臂血流量（FBF）的变化，以及这些参数的值是否与FBF的内侧和外侧平行变化。13名志愿者接受了前瞻性观察研究。在前臂评估组织氧合指数（TOI）、局部氧饱和度（rSO）、皮肤组织氧合（StO）和FBF值。短暂缺血终止后1至3分钟时内侧rSO值高于外侧rSO和各自的TOI值。随着短暂缺血的停止，FBF和StO值迅速增加，而在短暂缺血期间及之后内侧和外侧的值没有差异。短暂缺血后再灌注时，TOI和StO而非rSO同时反映了内侧和外侧FBF的变化。再灌注期间的肌肉组织氧合有利于将TOI和StO而非rSO用作替代参数。《医学调查杂志》64：228 - 232，2017年8月。
