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骨髓移植患者的脓肿分枝杆菌淋巴结炎

Mycobacterium abscessus lymphadenitis in bone marrow transplant patient.

作者信息

Khalid Muhammad, Ali Syed Asad

机构信息

Aga Khan University Hospital, Karachi.

出版信息

J Pak Med Assoc. 2017 Oct;67(10):1615-1617.

PMID:28955087
Abstract

Non-tuberculous mycobacteria (NTM) are acid-fast bacteria categorized into rapidly growing and slow growing mycobacteria. NTM are more common in transplant patients who are immunocompromised. Here we report the case of a post- bone marrow transplant adolescent male presenting with submandibular swelling and fever. The gland was excised and the histopathology showed chronic granulomatous inflammation. Culture grew Mycobacterium abscessus which was sensitive to amikacin, linezolid and clarithromycin. A good response was achieved on therapy.

摘要

非结核分枝杆菌(NTM)是一类抗酸菌,分为快速生长型和缓慢生长型分枝杆菌。NTM在免疫功能低下的移植患者中更为常见。在此,我们报告一例骨髓移植后的青少年男性病例,该患者出现下颌下肿胀和发热。切除了腺体,组织病理学显示为慢性肉芽肿性炎症。培养出脓肿分枝杆菌,该菌对阿米卡星、利奈唑胺和克拉霉素敏感。治疗取得了良好效果。

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引用本文的文献

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Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis.异基因造血干细胞移植受者中非结核分枝杆菌(NTM)感染的患病率和特征:系统评价和荟萃分析。
J Clin Immunol. 2023 Dec 22;44(1):23. doi: 10.1007/s10875-023-01615-3.