Badeeva Elena K, Santomenna Angelo, Gubaidullin Aidar T, Frolova Liliya V, Rogelj Snezna, Batyeva Elvira S, Sinyashin Oleg G
A.E. Arbuzov Institute of Organic and Physical Chemistry, Russian Academy of Sciences, Kazan Scientific Center, Kazan, Russian Federation.
Biology Department, New Mexico Institute of Mining and Technology, 801 Leroy Pl., Socorro, NM 87801, USA.
Phosphorus Sulfur Silicon Relat Elem. 2016;191(3):405-410. doi: 10.1080/10426507.2015.1091828. Epub 2016 Jan 14.
A new reaction of elemental phosphorus (P) with elemental sulfur and 1,3-propylene glycol in the presence of different amines has been investigated. Ammonium salts of O,O'- alkylenedithiophosphoric acids have been observed as main products of the reaction. Octathiotetraphosphetane ammonium salts were formed as minor products. The reaction is characterized by a complete conversion of white phosphorus and is not accompanied by the release of hydrogen sulfide. The crystal structure features's of diethylammonium salt of O,O'-propylenedithiophosphoric acid were determined using single crystal X-ray diffraction. Piperidinium salt of octathiotetraphosphetane in DMSO and DMF solutions possess significant antifungal activity against Candida albicans.
研究了单质磷（P）与单质硫及1,3 - 丙二醇在不同胺存在下的一种新反应。已观察到O,O'-亚烷基二硫代磷酸铵盐是该反应的主要产物。八硫代四磷杂环丁烷铵盐作为次要产物形成。该反应的特征是白磷完全转化，且不伴有硫化氢的释放。使用单晶X射线衍射确定了O,O'-丙撑二硫代磷酸二乙铵盐的晶体结构特征。八硫代四磷杂环丁烷的哌啶盐在二甲基亚砜（DMSO）和二甲基甲酰胺（DMF）溶液中对白色念珠菌具有显著的抗真菌活性。
