用人绝经期促性腺激素（hMG）以及hMG加人绒毛膜促性腺激素（hCG）治疗隐睾：临床、激素及超声评估

Treatment of undescended testes with hMG and hMG plus hCG: clinical, hormonal and sonographic evaluation.

作者信息

De Rosa G, Della Casa S, Corsello S M, Colabucci F, Rossodivita A, Ferdinandi A, Cecchini L

机构信息

Institute of Endocrinology, Catholic University School of Medicine, Rome, Italy.

出版信息

Ann Endocrinol (Paris). 1987;48(6):468-72.

PMID:2895604

Abstract

20 children (mean age 4, 6 yrs), of whom 13 had unilateral and 7 had bilateral cryptorchidism were treated with hMG: 40 I.U. three i.m. injections per week for six or eight weeks. Where there was no descent of testis, treatment was continued with hMG at the same dosage plus hCG 500 I.U. one i.m. injection per week for an additional four weeks. The children were tested for FSH, LH and Testosterone serum levels at the beginning of treatment and after 6, 8 and 14 weeks. We obtained testicular descent in 10 out of 20 cases treated. Ultrasonography enabled us to locate the undescended testes in all cases and to follow the response to treatment.

摘要

20名儿童（平均年龄4.6岁）接受了人绝经期促性腺激素（hMG）治疗，其中13名为单侧隐睾，7名为双侧隐睾：每周肌肉注射3次，每次40国际单位，共注射6至8周。若睾丸未下降，则继续使用相同剂量的hMG治疗，并加用绒毛膜促性腺激素（hCG），每周肌肉注射1次，每次500国际单位，再持续治疗4周。在治疗开始时以及治疗6周、8周和14周后，对这些儿童进行了血清促卵泡生成素（FSH）、促黄体生成素（LH）和睾酮水平检测。在接受治疗的20例病例中，有10例睾丸下降。超声检查使我们能够在所有病例中定位未降睾丸，并跟踪治疗反应。