Zhao Chang, Wang Ning, Wang Wenzhao, Xu Qiyong
School of Environment and Energy, Shenzhen Graduate School, Peking University, Shenzhen 518055, Guangdong, China.
Fairylands Environmental Sci-Tech. (Shenzhen) Go., Ltd., Shenzhen 518055, Guangdong, China.
Sheng Wu Gong Cheng Xue Bao. 2017 Sep 25;33(9):1596-1610. doi: 10.13345/j.cjb.170146.
Studies on biofilm regulation based on Lux type quorum sensing system in wastewater treatment have attracted much attention. The intervention of quorum sensing system includes both mechanisms of positive and negative control. The positive invigorating effect improves the efficiency of biofilm wastewater treatment, promotes the production of extracellular polymeric substance (EPS) and soluble microbial products (SMP), and increases the yield of biofilm. The negative weakening effect of quorum sensing can decompose the signal molecules needed in the process of biofilm formation, interrupts the gene expression process of biofilm formation, and inhibits the formation of biofilm on MBR membrane surface effectively. The further study of the structure and mechanism of N-acyl homoserine lactone (AHLs), the immobilization technology and application of quorum quenching bacteria, the synergistic effect verification of different biofouling control methods and the application feasibility of quorum sensing system based technology in more wastewater treatment fields are the next important researches to explore.
基于Lux型群体感应系统的生物膜调控在污水处理中的研究备受关注。群体感应系统的干预包括正调控和负调控机制。正调控效应可提高生物膜污水处理效率，促进胞外聚合物（EPS）和可溶性微生物产物（SMP）的产生，并增加生物膜产量。群体感应的负调控效应可分解生物膜形成过程中所需的信号分子，中断生物膜形成的基因表达过程，并有效抑制MBR膜表面生物膜的形成。进一步研究N-酰基高丝氨酸内酯（AHLs）的结构和作用机制、群体淬灭细菌的固定化技术及应用、不同生物污染控制方法的协同效应验证以及基于群体感应系统的技术在更多污水处理领域的应用可行性，是接下来需要探索的重要研究方向。
