通过计算机断层扫描检测酒精性脂肪肝
Detection of alcohol-induced fatty liver by computerized tomography.
作者信息
Allaway S L, Ritchie C D, Robinson D, Seear T, Reznek R, Fry I K, Thompson G R
机构信息
BUPA Medical Research.
出版信息
J R Soc Med. 1988 Mar;81(3):149-51. doi: 10.1177/014107688808100310.
Computerized tomographic (CT) scanning of the liver was undertaken in 17 occasional and 19 heavy drinkers undergoing health screening. The median attenuation value of the liver (CT number) in occasional drinkers with normal liver function tests was 54.4 compared with 25.9 in the heavy drinkers (P less than 0.001). Fourteen of the heavy drinkers had a CT number below the lowest value observed in occasional drinkers with normal liver function, indicating reduced liver density due to fatty change. Serum gamma-glutamyl transpeptidase was normal in 36% of these individuals. A rise in CT number was observed in 4 out of 5 heavy drinkers who underwent a second scan after decreasing their alcohol consumption. These findings suggest that CT scanning provides a noninvasive and convenient method of screening for a fatty liver, which occurred to a variable degree in over 70% of the men who admitted to regularly taking 8 or more alcoholic drinks per day.
对17名偶尔饮酒者和19名接受健康筛查的重度饮酒者进行了肝脏计算机断层扫描（CT）。肝功能检查正常的偶尔饮酒者肝脏的中位衰减值（CT值）为54.4，而重度饮酒者为25.9（P<0.001）。14名重度饮酒者的CT值低于肝功能正常的偶尔饮酒者观察到的最低值，表明因脂肪变性导致肝脏密度降低。这些个体中36%的血清γ-谷氨酰转肽酶正常。5名重度饮酒者在减少饮酒量后进行第二次扫描，其中4人观察到CT值升高。这些发现表明，CT扫描为筛查脂肪肝提供了一种非侵入性且便捷的方法，在承认每天经常饮用8杯或更多酒精饮料的男性中，超过70%的人出现了不同程度的脂肪肝。
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