a Department of Adult , Child and Midwifery, School of Health and Education, Middlesex University , London , UK.
b Faculty of Rehabilitation, University of Alberta , Edmonton , Alberta , Canada.
Assist Technol. 2019;31(1):1-8. doi: 10.1080/10400435.2017.1340360. Epub 2017 Sep 29.
The objective of this article is to examine dynamic changes of ischial blood perfusion during sacral nerve root stimulation against surface functional electrical stimulation (FES). Fourteen adults with suprasacral spinal cord injury (SCI) were recruited. The gluteal maximus was activated by surface FES or stimulating sacral nerve roots by functional magnetic stimulation (FMS) or a sacral anterior root stimulator implant (SARS). Ischial skin index of hemoglobin (IHB) and oxygenation (IOX) was measured.Skin blood perfusion was significantly higher during FMS than the baseline (IHB 1.05 ± 0.21 before vs.1.08 ± 0.02 during stimulation, p = 0.03; IOX 0.18 ± 0.21 before vs. 0.46 ± 0.30, p = 0.01 during stimulation). Similarly, when using the SARS implant, we also observed blood perfusion significantly increased (IHB 1.01 ± 0.02 before vs.1.07 ± 0.02 during stimulation, p = 0.003; IOX 0.79 ± 0.81 before vs. 2.2 ± 1.21 during stimulation, p = 0.036). Among four participants who completed both the FMS and FES studies, the magnitude of increase in both parameters was significantly higher during FMS. This study demonstrates sacral nerve root stimulation confer better benefit on blood perfusion than applying traditional FES in SCI population.
本文旨在探讨在表面功能性电刺激（FES）作用下，骶神经根刺激时坐骨血灌注的动态变化。共招募了 14 名上运动神经元完全性脊髓损伤（SCI）成人患者。使用表面 FES 或功能磁刺激（FMS）或骶前根刺激器植入（SARS）激活臀大肌。测量坐骨皮肤血红蛋白指数（IHB）和氧合指数（IOX）。FMS 刺激时的皮肤血流灌注明显高于基线水平（IHB 在刺激前为 1.05 ± 0.21，刺激时为 1.08 ± 0.02，p = 0.03；IOX 在刺激前为 0.18 ± 0.21，刺激时为 0.46 ± 0.30，p = 0.01）。同样，当使用 SARS 植入物时，我们也观察到血流灌注明显增加（IHB 在刺激前为 1.01 ± 0.02，刺激时为 1.07 ± 0.02，p = 0.003；IOX 在刺激前为 0.79 ± 0.81，刺激时为 2.2 ± 1.21，p = 0.036）。在完成 FMS 和 FES 研究的 4 名参与者中，这两个参数在 FMS 刺激期间的增加幅度明显更高。本研究表明，与传统的 FES 相比，骶神经根刺激在 SCI 人群中更能改善血灌注。
