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两例产前诊断的膜周部和肌部室间隔瘤

Two Cases of Prenatally Diagnosed Membranous and Muscular Ventricular Septal Aneurysms.

作者信息

Ivanitskaya Olga, Andreeva Elena, Odegova Natalia

机构信息

Department of Medical Genetics, Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia.

出版信息

J Ultrasound Med. 2018 Apr;37(4):1039-1042. doi: 10.1002/jum.14440. Epub 2017 Sep 29.

Abstract

A ventricular septal aneurysm is a rare heart defect located in the muscular or membranous part of the septum. Muscular ventricular septal aneurysms are usually isolated, with a favorable prognosis. Membranous ventricular septal aneurysms are often associated with other heart anomalies, could result in serious complications, and may require surgical treatment. We describe 2 cases of prenatally diagnosed ventricular septal aneurysms: an isolated membranous ventricular septal aneurysm with a good outcome, which was initially misdiagnosed as an atrioventricular septal defect; and a muscular ventricular septal aneurysm associated with a hypoplastic aortic arch and severe hydrocephaly, which resulted in termination of the pregnancy. To our knowledge, the combination of a muscular ventricular septal aneurysm with an extracardiac anomaly has not been reported previously.

摘要

室间隔瘤是一种罕见的心脏缺陷,位于室间隔的肌性或膜性部分。肌性室间隔瘤通常为孤立性,预后良好。膜性室间隔瘤常与其他心脏异常相关,可导致严重并发症,可能需要手术治疗。我们描述了2例产前诊断的室间隔瘤病例:1例孤立性膜性室间隔瘤,预后良好,最初被误诊为房室间隔缺损;另1例肌性室间隔瘤合并主动脉弓发育不全和严重脑积水,导致终止妊娠。据我们所知,肌性室间隔瘤合并心外异常的情况此前尚未见报道。

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