Ivanitskaya Olga, Andreeva Elena, Odegova Natalia
Department of Medical Genetics, Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia.
J Ultrasound Med. 2018 Apr;37(4):1039-1042. doi: 10.1002/jum.14440. Epub 2017 Sep 29.
A ventricular septal aneurysm is a rare heart defect located in the muscular or membranous part of the septum. Muscular ventricular septal aneurysms are usually isolated, with a favorable prognosis. Membranous ventricular septal aneurysms are often associated with other heart anomalies, could result in serious complications, and may require surgical treatment. We describe 2 cases of prenatally diagnosed ventricular septal aneurysms: an isolated membranous ventricular septal aneurysm with a good outcome, which was initially misdiagnosed as an atrioventricular septal defect; and a muscular ventricular septal aneurysm associated with a hypoplastic aortic arch and severe hydrocephaly, which resulted in termination of the pregnancy. To our knowledge, the combination of a muscular ventricular septal aneurysm with an extracardiac anomaly has not been reported previously.
室间隔瘤是一种罕见的心脏缺陷，位于室间隔的肌性或膜性部分。肌性室间隔瘤通常为孤立性，预后良好。膜性室间隔瘤常与其他心脏异常相关，可导致严重并发症，可能需要手术治疗。我们描述了2例产前诊断的室间隔瘤病例：1例孤立性膜性室间隔瘤，预后良好，最初被误诊为房室间隔缺损；另1例肌性室间隔瘤合并主动脉弓发育不全和严重脑积水，导致终止妊娠。据我们所知，肌性室间隔瘤合并心外异常的情况此前尚未见报道。
