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[慢性静脉疾病中与健康相关的生活质量:系统文献综述]

[Health related quality of life in chronic venous disease: Systematic literature review].

作者信息

Zenati N, Bosson J L, Blaise S, Carpentier P

机构信息

Clinique universitaire de médecine vasculaire, Grenoble-Alpes, CHU de Grenoble, 38043 Grenoble cedex 09, France.

Centre d'investigation clinique DMIS Pavillon-Taillefer, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France.

出版信息

J Med Vasc. 2017 Oct;42(5):290-300. doi: 10.1016/j.jdmv.2017.07.001. Epub 2017 Sep 1.

DOI:10.1016/j.jdmv.2017.07.001
PMID:28964388
Abstract

OBJECTIVE

Excepting life-threatening situations, improvement of health-related quality-of-life is the main therapeutic goal in chronic disease. The purpose of this review was to study the different ways of assessing Quality-of-Life (QoL) in patients with chronic venous disease (CVD) (CEAP classes C3 to C6).

METHODS

A literature search was conducted with three databases: MEDLINE, WEB OF SCIENCE and COCHRANE LIBRARY in order to identify articles with the PRISMA reporting guidelines. Then we compared psychometric performance of general and specific QoL questionnaires for a French population with CVD.

RESULTS

A total of 481 articles were identified, from which 25 were selected and analyzed. CIVIQ 20, CIVIQ 14 and VEINES Qol/sym are the specific health related QoL scales validated for a French population with CVD. VEINES Qol/sym was specifically validated in patients with leg ulcer or post-thrombotic syndrome (PTS). CIVIQ 14 is a CIVIQ 20 optimized to be used more widely in international studies and validated in milder forms of the CVD spectrum (C0 à C4). The general health related QoL scales are SF-36, SF-12 and EQ-5D. EQ-5D is simple and provides health state utility values.

CONCLUSION

CIVIQ 14 is a simple specific health-related QoL scale for less severe CVD. VEINES Qol/sym was developed for severe CVD and PTS but clinically relevant point scales remain to be assessed. EQ-5D is a generic scale to be preferred to assess economic impact based on a cost-utility analysis.

摘要

目的

除危及生命的情况外,改善与健康相关的生活质量是慢性病治疗的主要目标。本综述的目的是研究评估慢性静脉疾病(CVD)(CEAP分级C3至C6)患者生活质量(QoL)的不同方法。

方法

使用三个数据库进行文献检索:MEDLINE、科学网和考克兰图书馆,以便根据PRISMA报告指南识别文章。然后,我们比较了针对法国CVD人群的一般和特定QoL问卷的心理测量性能。

结果

共识别出481篇文章,从中选择并分析了25篇。CIVIQ 20、CIVIQ 14和VEINES Qol/sym是针对法国CVD人群验证的特定健康相关QoL量表。VEINES Qol/sym在腿部溃疡或血栓后综合征(PTS)患者中得到了专门验证。CIVIQ 14是CIVIQ 20的优化版本,更广泛地用于国际研究,并在较轻形式的CVD谱系(C0至C4)中得到验证。一般健康相关QoL量表为SF-36、SF-12和EQ-5D。EQ-5D简单,可提供健康状态效用值。

结论

CIVIQ 14是一种用于不太严重的CVD的简单特定健康相关QoL量表。VEINES Qol/sym是为严重CVD和PTS开发的,但临床相关的评分量表仍有待评估。EQ-5D是一种通用量表,基于成本效用分析,在评估经济影响时更受青睐。

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J Med Vasc. 2017 Oct;42(5):290-300. doi: 10.1016/j.jdmv.2017.07.001. Epub 2017 Sep 1.
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Healing Process, Pain, and Health-Related Quality of Life in Patients with Venous Leg Ulcers Treated with Fish Collagen Gel: A 12-Week Randomized Single-Center Study.鱼胶原蛋白凝胶治疗静脉性下肢溃疡患者的愈合过程、疼痛和健康相关生活质量:一项 12 周随机单中心研究。
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