Ramalho Miguel, Ramalho Joana
Department of Radiology, Hospital Garcia de Orta, Avenida Torrado da Silva, 2805-267 Almada, Portugal.
Department of Neuroradiology, Centro Hospitalar de Lisboa Central, Rua José António Serrano, 1150-199 Lisboa, Portugal.
Magn Reson Imaging Clin N Am. 2017 Nov;25(4):755-764. doi: 10.1016/j.mric.2017.06.006. Epub 2017 Sep 8.
Gadolinium-based contrast agents have been considered extremely safe drugs with a low incidence of acute adverse reactions. Most of the reactions are mild and physiologic. However, despite being extremely rare, acute severe adverse reactions, including anaphylaxis, may occur. In this article adverse reactions are discussed with regard to their classification, pathophysiology, symptoms, and risk factors.
钆基造影剂被认为是极其安全的药物,急性不良反应发生率低。大多数反应是轻微的生理性反应。然而,尽管极为罕见,但仍可能发生包括过敏反应在内的急性严重不良反应。本文将从不良反应的分类、病理生理学、症状及危险因素方面进行讨论。