Damask Cecelia
Private Practice, Florida Hospital Altamonte Springs, 795 Primera Boulevard Suite 1031, Lake Mary, FL 32746, USA; University of Central Florida College of Medicine, 6850 Lake Nona Boulevard, Orlando, FL 32827, USA.
Otolaryngol Clin North Am. 2017 Dec;50(6):1153-1165. doi: 10.1016/j.otc.2017.08.012. Epub 2017 Sep 28.
Polysensitization, sensitization to more than one allergen, is a common feature of patients with allergic rhinitis, and may be a risk factor for subsequent development of allergic diseases, especially allergic asthma. However, a polysensitized patient does not necessarily have polyallergy, a documented, causal relationship between exposure to 2 or more specific, sensitizing allergens and the subsequent occurrence of relevant clinical symptoms of allergy. Allergen immunotherapy treatment strategy for the polysensitized patient in Europe is to treat the single or 2 most clinically relevant allergen(s), whereas patients in the United States are usually treated for all potential clinically relevant allergens.
多致敏现象，即对一种以上过敏原致敏，是过敏性鼻炎患者的常见特征，可能是后续发生过敏性疾病尤其是过敏性哮喘的危险因素。然而，多致敏患者不一定患有多重过敏症，多重过敏症指接触两种或更多特定致敏过敏原与随后出现相关过敏临床症状之间存在记录在案的因果关系。在欧洲，针对多致敏患者的变应原免疫治疗策略是治疗单一或两种临床上最相关的变应原，而在美国，患者通常会针对所有潜在的临床上相关的变应原进行治疗。
