Koo Soo Kweon, Kwon Soon Bok, Moon Ji Seung, Lee Sang Hoon, Lee Ho Byung, Lee Sang Jun
Department of Otorhinolaryngology, Busan Saint Mary's Hospital, Busan, South Korea.
Department of Language and Information, College of Humanities, Pusan National University, South Korea.
Auris Nasus Larynx. 2018 Aug;45(4):777-782. doi: 10.1016/j.anl.2017.09.005. Epub 2017 Sep 28.
Snoring is an important clinical feature of obstructive sleep apnea (OSA), and recent studies suggest that the acoustic quality of snoring sounds is markedly different in drug-induced sleep compared with natural sleep. However, considering differences in sound recording methods and analysis parameters, further studies are required. This study explored whether acoustic analysis of drug-induced sleep is useful as a screening test that reflects the characteristics of natural sleep in snoring patients.
The snoring sounds of 30 male subjects (mean age=41.8years) were recorded using a smartphone during natural and induced sleep, with the site of vibration noted during drug-induced sleep endoscopy (DISE); then, we compared the sound intensity (dB), formant frequencies, and spectrograms of snoring sounds.
Regarding the intensity of snoring sounds, there were minor differences within the retrolingual level obstruction group, but there was no significant difference between natural and induced sleep at either obstruction site. There was no significant difference in the F and F formant frequencies of snoring sounds between natural sleep and induced sleep at either obstruction site. Compared with natural sleep, induced sleep was slightly more irregular, with a stronger intensity on the spectrogram, but the spectrograms showed the same pattern at both obstruction sites.
Although further studies are required, the spectrograms and formant frequencies of the snoring sounds of induced sleep did not differ significantly from those of natural sleep, and may be used as a screening test that reflects the characteristics of natural sleep according to the obstruction site.
打鼾是阻塞性睡眠呼吸暂停（OSA）的一项重要临床特征，近期研究表明，与自然睡眠相比，药物诱导睡眠时的鼾声声学特性存在显著差异。然而，考虑到录音方法和分析参数的差异，仍需进一步研究。本研究探讨了药物诱导睡眠的声学分析作为一种反映打鼾患者自然睡眠特征的筛查测试是否有用。
使用智能手机记录30名男性受试者（平均年龄 = 41.8岁）在自然睡眠和诱导睡眠期间的鼾声，并在药物诱导睡眠内镜检查（DISE）期间记录振动部位；然后，我们比较了鼾声的声强（dB）、共振峰频率和频谱图。
关于鼾声强度，舌后水平阻塞组内存在细微差异，但在任一阻塞部位，自然睡眠和诱导睡眠之间均无显著差异。在任一阻塞部位，自然睡眠和诱导睡眠时鼾声的F1和F2共振峰频率均无显著差异。与自然睡眠相比，诱导睡眠稍不规则，频谱图上的强度更强，但两个阻塞部位的频谱图显示出相同的模式。
尽管仍需进一步研究，但诱导睡眠时鼾声的频谱图和共振峰频率与自然睡眠时相比无显著差异，可作为一种根据阻塞部位反映自然睡眠特征的筛查测试。
