使用具有差异化刚性的棒状结构改善胸椎后凸畸形的矫正,用于青少年特发性脊柱侧凸的手术治疗。

Improved restoration of thoracic kyphosis using a rod construct with differentiated rigidity in the surgical treatment of adolescent idiopathic scoliosis.

机构信息

Department of Orthopaedic Surgery, Spine Unit, University Hospital of Copenhagen, Denmark.

Department of Orthopedics and Scoliosis Surgery, Texas Children's Hospital, Houston, Texas; and.

出版信息

Neurosurg Focus. 2017 Oct;43(4):E6. doi: 10.3171/2017.7.FOCUS17351.

Abstract

OBJECTIVE The objective of this study was to compare postoperative sagittal alignment among 3 rod constructs with different rigidity profiles. METHODS This was a dual-center retrospective cohort study involving 2 consecutive cohorts in which patients were surgically treated for adolescent idiopathic scoliosis. Lenke Type 5 curves were excluded. Patients were operated on with all-pedicle screw instrumentation using 3 different rod constructs. The first group was operated on using a hybrid construct (HC) consisting of a normal circular rod on the convex side and a beam-like rod (BR) on the concave side. The second group was operated on with a standard construct (SC) using bilateral BRs in the full length of the fusion. The third group was operated on with a modified construct (MC). The modified rods have a beam-like shape in the caudal portion, but in the cranial 2 or 3 fusion levels the rod transitions to a circular shape with a smaller anteroposterior diameter. Radiographs were analyzed preoperatively and at the first postoperative follow-up (range 1-8 weeks). The primary outcome was pre- to postoperative change in thoracic kyphosis (TK), and the secondary outcome was the ability to achieve postoperative TK within the normal range. RESULTS The HC, SC, and MC groups included 23, 70, and 46 patients, respectively. The 3 groups did not differ significantly in preoperative demographic or radiographic parameters. The mean ± standard deviation of the preoperative main curve was 60.7° ± 12.6°, and the mean of curve correction was 62.9% ± 10.4% with no significant difference among groups (p ≥ 0.680). The groups did not differ significantly in coronal balance or proximal or thoracolumbar curve correction (p ≥ 0.189). Mean postoperative TK was 23.1° ± 6.3°, 19.6° ± 7.6°, and 23.4° ± 6.9° in the HC, SC and MC groups, respectively (p = 0.013), and the mean change in TK was -3.5° ± 11.3°, -7.1° ± 11.6°, and 0.1° ± 10.9°, respectively (p = 0.005). The MC group had significantly higher postoperative TK and less loss of TK compared with the SC group (p ≤ 0.018). Postoperative TK ≤ 10° was found in 12 patients (17%) in the SC group, 1 patient (5%) in the HC group, and 1 patient (2%) in the MC group (p = 0.021). There were no differences in proximal alignment, thoracolumbar alignment, or sagittal vertical axis (p ≥ 0.249). Lumbar lordosis was 58.9° ± 11.2° in the HC group versus 52.0° ± 1.3° and 55.0° ± 11.0° and the SC and MC groups, respectively (p = 0.040). CONCLUSIONS In the 3 rod constructs with different rigidity profiles, significantly better restoration of kyphosis was achieved with the use of bilateral modified rods compared with bilateral standard rods. In the MC and HC groups, the rate of severe postoperative hypokyphosis was significantly lower than in the SC group. This is the first study to describe the clinical use of a rod with a reduced proximal diameter and show marked radiographic improvement in sagittal alignment.

摘要

目的

本研究旨在比较 3 种不同刚性杆构建体的术后矢状面排列。

方法

这是一项双中心回顾性队列研究,纳入了 2 个连续队列,队列中的患者均接受青少年特发性脊柱侧凸的手术治疗。排除 Lenke 5 型曲线。使用全椎弓根螺钉器械,使用 3 种不同的杆构建体对患者进行手术治疗。第一组使用混合构建体(HC)进行手术,凸侧为常规圆形杆,凹侧为梁状杆(BR)。第二组使用双侧 BR 的标准构建体(SC)进行手术,全长融合。第三组使用改良构建体(MC)进行手术。改良杆的尾部为梁状,而在头侧的 2 或 3 个融合水平,杆过渡为具有较小前后直径的圆形。在术前和术后首次随访(1-8 周)时分析 X 线片。主要结局为术前到术后胸椎后凸(TK)的变化,次要结局为术后 TK 达到正常范围的能力。

结果

HC、SC 和 MC 组分别包括 23、70 和 46 例患者。3 组在术前人口统计学或影像学参数方面无显著差异。术前主曲线平均±标准差为 60.7°±12.6°,平均曲线矫正率为 62.9%±10.4%,各组间无显著差异(p≥0.680)。各组在冠状平衡或近端和胸腰椎曲线矫正方面无显著差异(p≥0.189)。HC、SC 和 MC 组术后 TK 平均值分别为 23.1°±6.3°、19.6°±7.6°和 23.4°±6.9°(p=0.013),TK 平均变化分别为-3.5°±11.3°、-7.1°±11.6°和 0.1°±10.9°(p=0.005)。MC 组术后 TK 明显更高,SC 组 TK 丢失明显减少(p≤0.018)。SC 组有 12 例(17%)患者术后 TK≤10°,HC 组 1 例(5%)患者,MC 组 1 例(2%)患者(p=0.021)。近端排列、胸腰椎排列和矢状垂直轴无差异(p≥0.249)。HC 组腰椎前凸角为 58.9°±11.2°,而 SC 组和 MC 组分别为 52.0°±1.3°和 55.0°±11.0°(p=0.040)。

结论

在 3 种不同刚性杆构建体中,与双侧标准杆相比,双侧改良杆可显著更好地恢复后凸。与 SC 组相比,MC 和 HC 组术后严重低后凸的发生率明显更低。这是首次描述使用近端直径减小的杆的临床应用,并显示出明显的矢状面排列的影像学改善。

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