小鼠背外侧膝状核的组织结构
Organization of the dorsal lateral geniculate nucleus in the mouse.
作者信息
Kerschensteiner Daniel, Guido William
机构信息
Department of Ophthalmology and Visual Sciences,Washington University School of Medicine,Saint Louis,Missouri 63110.
Department of Anatomical Sciences and Neurobiology,University of Louisville School of Medicine,Louisville,Kentucky 40292.
出版信息
Vis Neurosci. 2017 Jan;34:E008. doi: 10.1017/S0952523817000062.
Abstract
The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the principal conduit for visual information from retina to visual cortex. Viewed initially as a simple relay, recent studies in the mouse reveal far greater complexity in the way input from the retina is combined, transmitted, and processed in dLGN. Here we consider the structural and functional organization of the mouse retinogeniculate pathway by examining the patterns of retinal projections to dLGN and how they converge onto thalamocortical neurons to shape the flow of visual information to visual cortex.
摘要
丘脑的背外侧膝状核（dLGN）是视觉信息从视网膜传输到视觉皮层的主要通道。最初被视为一个简单的中继站，最近对小鼠的研究揭示了视网膜输入在dLGN中组合、传输和处理方式的复杂性要高得多。在这里，我们通过研究视网膜向dLGN的投射模式以及它们如何汇聚到丘脑皮质神经元上以塑造视觉信息流向视觉皮层的方式，来探讨小鼠视网膜膝状体通路的结构和功能组织。
相似文献
1
Organization of the dorsal lateral geniculate nucleus in the mouse.小鼠背外侧膝状核的组织结构
Vis Neurosci. 2017 Jan;34:E008. doi: 10.1017/S0952523817000062.
2
Corticothalamic Axons Are Essential for Retinal Ganglion Cell Axon Targeting to the Mouse Dorsal Lateral Geniculate Nucleus.皮质丘脑轴突对于视网膜神经节细胞轴突靶向小鼠背外侧膝状核至关重要。
J Neurosci. 2016 May 11;36(19):5252-63. doi: 10.1523/JNEUROSCI.4599-15.2016.
3
Not a one-trick pony: Diverse connectivity and functions of the rodent lateral geniculate complex.并非一招鲜：啮齿动物外侧膝状体复合体的多样连接性与功能
Vis Neurosci. 2017 Jan;34:E012. doi: 10.1017/S0952523817000098.
4
Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus.大脑皮层和丘脑之间的相互联系有助于视网膜轴突靶向外侧膝状体的背核。
Cereb Cortex. 2018 Apr 1;28(4):1168-1182. doi: 10.1093/cercor/bhx028.
5
The absence of retinal input disrupts the development of cholinergic brainstem projections in the mouse dorsal lateral geniculate nucleus.视网膜输入的缺失会破坏小鼠背外侧膝状体核胆碱能脑干投射的发育。
Neural Dev. 2018 Dec 12;13(1):27. doi: 10.1186/s13064-018-0124-7.
6
Retinal and Tectal "Driver-Like" Inputs Converge in the Shell of the Mouse Dorsal Lateral Geniculate Nucleus.视网膜和顶盖“驱动样”输入汇聚于小鼠背外侧膝状核的壳区。
J Neurosci. 2015 Jul 22;35(29):10523-34. doi: 10.1523/JNEUROSCI.3375-14.2015.
7
Limited functional convergence of eye-specific inputs in the retinogeniculate pathway of the mouse.小鼠视网膜-视顶盖通路中眼特异性输入的功能有限趋同。
Neuron. 2021 Aug 4;109(15):2457-2468.e12. doi: 10.1016/j.neuron.2021.05.036. Epub 2021 Jun 18.
8
'Hidden lamination' in the dorsal lateral geniculate nucleus: the functional organization of this thalamic region in the rat.背侧外侧膝状核中的“隐藏分层”：大鼠丘脑该区域的功能组织
Brain Res. 1988 Apr-Jun;472(2):119-37. doi: 10.1016/0165-0173(88)90017-3.
9
Functional convergence of on-off direction-selective ganglion cells in the visual thalamus.视觉丘脑中开-关方向选择性神经节细胞的功能趋同。
Curr Biol. 2022 Jul 25;32(14):3110-3120.e6. doi: 10.1016/j.cub.2022.06.023. Epub 2022 Jul 5.
10
CKAMP44 controls synaptic function and strength of relay neurons during early development of the dorsal lateral geniculate nucleus.CKAMP44 在背外侧膝状体核早期发育过程中控制着中继神经元的突触功能和强度。
J Physiol. 2022 Aug;600(15):3549-3565. doi: 10.1113/JP283172. Epub 2022 Jul 17.
引用本文的文献
1
Cell-type specific binocular interactions in mouse visual thalamus.小鼠视觉丘脑的细胞类型特异性双眼相互作用。
iScience. 2025 Jun 19;28(7):112956. doi: 10.1016/j.isci.2025.112956. eCollection 2025 Jul 18.
2
Morphological and Molecular Distinctions of Parallel Processing Streams Reveal Two Koniocellular Pathways in the Tree Shrew DLGN.并行处理流的形态学和分子差异揭示了树鼩背外侧膝状体核中的两条小细胞通路。
eNeuro. 2025 Jul 10;12(7). doi: 10.1523/ENEURO.0522-24.2025. Print 2025 Jul.
3
Experience-dependent plasticity of multiple receptive field properties in lateral geniculate binocular neurons during the critical period.关键期内外侧膝状体双眼神经元多种感受野特性的经验依赖性可塑性。
Front Cell Neurosci. 2025 Apr 28;19:1574505. doi: 10.3389/fncel.2025.1574505. eCollection 2025.
4
Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension.胞磷胆碱与辅酶Q10联合应用对高眼压小鼠模型的神经保护作用
Antioxidants (Basel). 2024 Dec 24;14(1):4. doi: 10.3390/antiox14010004.
5
Inner Structure of the Lateral Geniculate Complex of Adult and Newborn .成年和新生动物外侧膝状体复合体的内部结构。
Int J Mol Sci. 2024 Jul 18;25(14):7855. doi: 10.3390/ijms25147855.
6
Development of ocular dominance columns across rodents and other species: revisiting the concept of critical period plasticity.眼优势柱在啮齿类动物和其他物种中的发育：再探关键期可塑性概念。
Front Neural Circuits. 2024 Jul 5;18:1402700. doi: 10.3389/fncir.2024.1402700. eCollection 2024.
7
Enhanced Synaptic Inhibition in the Dorsolateral Geniculate Nucleus in a Mouse Model of Glaucoma.青光眼小鼠模型中外侧膝状体核的突触抑制增强。
eNeuro. 2024 Jul 11;11(7). doi: 10.1523/ENEURO.0263-24.2024. Print 2024 Jul.
8
Mechanism of an Intrinsic Oscillation in Rat Geniculate Interneurons.大鼠膝状体内神经元内在振荡的机制。
bioRxiv. 2024 Jun 8:2024.06.06.597830. doi: 10.1101/2024.06.06.597830.
9
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.由 FUS 引发的聚集和传播导致的额颞叶痴呆样疾病进展。
Mol Neurodegener. 2024 Jun 11;19(1):46. doi: 10.1186/s13024-024-00737-5.
10
A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis.一个顺式调控模块是视网膜神经节细胞发生和轴突发生的基础。
Cell Rep. 2024 Jun 25;43(6):114291. doi: 10.1016/j.celrep.2024.114291. Epub 2024 May 31.
本文引用的文献
1
Contributions of Retinal Ganglion Cells to Subcortical Visual Processing and Behaviors.视网膜神经节细胞对皮质下视觉处理和行为的贡献。
Annu Rev Vis Sci. 2015 Nov 24;1:291-328. doi: 10.1146/annurev-vision-082114-035502.
2
Different Modes of Visual Integration in the Lateral Geniculate Nucleus Revealed by Single-Cell-Initiated Transsynaptic Tracing.单细胞起始的跨突触示踪揭示外侧膝状核中视觉整合的不同模式
Neuron. 2017 Feb 22;93(4):767-776.e6. doi: 10.1016/j.neuron.2017.01.028.
3
Diverse Central Projection Patterns of Retinal Ganglion Cells.视网膜神经节细胞的多样中枢投射模式。
Cell Rep. 2017 Feb 21;18(8):2058-2072. doi: 10.1016/j.celrep.2017.01.075.
4
Visual Functions of the Thalamus.丘脑的视觉功能
Annu Rev Vis Sci. 2015 Nov;1:351-371. doi: 10.1146/annurev-vision-082114-035920.
5
A Comparison of Visual Response Properties in the Lateral Geniculate Nucleus and Primary Visual Cortex of Awake and Anesthetized Mice.清醒和麻醉小鼠外侧膝状体核与初级视觉皮层视觉反应特性的比较
J Neurosci. 2016 Nov 30;36(48):12144-12156. doi: 10.1523/JNEUROSCI.1741-16.2016.
6
Synaptic Contributions to Receptive Field Structure and Response Properties in the Rodent Lateral Geniculate Nucleus of the Thalamus.突触对啮齿动物丘脑外侧膝状体核感受野结构和反应特性的贡献。
J Neurosci. 2016 Oct 26;36(43):10949-10963. doi: 10.1523/JNEUROSCI.1045-16.2016.
7
M1 ipRGCs Influence Visual Function through Retrograde Signaling in the Retina.M1型内在光敏视网膜神经节细胞通过视网膜中的逆行信号传导影响视觉功能。
J Neurosci. 2016 Jul 6;36(27):7184-97. doi: 10.1523/JNEUROSCI.3500-15.2016.
8
Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.两对ON和OFF视网膜神经节细胞由转录因子表达的交叉模式定义。
Cell Rep. 2016 May 31;15(9):1930-44. doi: 10.1016/j.celrep.2016.04.069. Epub 2016 May 19.
9
Shared and distinct retinal input to the mouse superior colliculus and dorsal lateral geniculate nucleus.小鼠上丘和背外侧膝状核的共享和独特视网膜输入。
J Neurophysiol. 2016 Aug 1;116(2):602-10. doi: 10.1152/jn.00227.2016. Epub 2016 May 11.
10
Target-Specific Glycinergic Transmission from VGluT3-Expressing Amacrine Cells Shapes Suppressive Contrast Responses in the Retina.来自表达VGluT3的无长突细胞的靶向甘氨酸能传递塑造视网膜中的抑制性对比度反应。
Cell Rep. 2016 May 17;15(7):1369-1375. doi: 10.1016/j.celrep.2016.04.025. Epub 2016 May 5.
Zotero 插件