Kerschensteiner Daniel, Guido William
Department of Ophthalmology and Visual Sciences,Washington University School of Medicine,Saint Louis,Missouri 63110.
Department of Anatomical Sciences and Neurobiology,University of Louisville School of Medicine,Louisville,Kentucky 40292.
Vis Neurosci. 2017 Jan;34:E008. doi: 10.1017/S0952523817000062.
The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the principal conduit for visual information from retina to visual cortex. Viewed initially as a simple relay, recent studies in the mouse reveal far greater complexity in the way input from the retina is combined, transmitted, and processed in dLGN. Here we consider the structural and functional organization of the mouse retinogeniculate pathway by examining the patterns of retinal projections to dLGN and how they converge onto thalamocortical neurons to shape the flow of visual information to visual cortex.
丘脑的背外侧膝状核(dLGN)是视觉信息从视网膜传输到视觉皮层的主要通道。最初被视为一个简单的中继站,最近对小鼠的研究揭示了视网膜输入在dLGN中组合、传输和处理方式的复杂性要高得多。在这里,我们通过研究视网膜向dLGN的投射模式以及它们如何汇聚到丘脑皮质神经元上以塑造视觉信息流向视觉皮层的方式,来探讨小鼠视网膜膝状体通路的结构和功能组织。