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脓疱性关节骨炎(园崎综合征):一例罕见病例报告。

Pustulotic arthro-osteitis (Sonozaki Syndrome): A rare case report.

作者信息

Resorlu Hatice, Inceer Besir Sahin, Kılıc Sevilay, Isık Selda

机构信息

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.

Department of Dermatology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.

出版信息

J Back Musculoskelet Rehabil. 2017 Sep 22;30(5):1137-1139. doi: 10.3233/BMR-169646.

DOI:10.3233/BMR-169646
PMID:28968231
Abstract

Pustulotic arthro-osteitis is a rare disease involving the skin and musculoskeletal system that was first described by Sonozaki. Onset is frequently seen at age 30-40. The prevalences between the sexes are similar. Palmoplantar pustulosis and sternoclavicular joint involvement are the most typical findings. It may be difficult to distinguish seronegative spondyloarthropathies and SAPHO syndrome due to sacroiliac joint, vertebral column and peripheral joint involvement. Arthritis being non-erosive and short-lived in character and the absence of deformity or contracture in the joints are significant clinical characteristics. Anti-inflammatory and immunesuppressive drugs are used in the treatment of the disease, the course of which involves remission and flare-ups. We describe the case of a 43-year-old male patient diagnosed with pustulotic arthro-osteitis.

摘要

脓疱性关节骨炎是一种累及皮肤和肌肉骨骼系统的罕见疾病,最初由园崎描述。发病常见于30至40岁。男女患病率相似。掌跖脓疱病和胸锁关节受累是最典型的表现。由于骶髂关节、脊柱和外周关节受累,可能难以区分血清阴性脊柱关节病和SAPHO综合征。关节炎具有非侵蚀性和病程短暂的特点,且关节无畸形或挛缩是重要的临床特征。治疗该疾病使用抗炎和免疫抑制药物,病程包括缓解期和发作期。我们描述了一名43岁男性脓疱性关节骨炎患者的病例。

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Pustulotic arthro-osteitis (Sonozaki Syndrome): A rare case report.脓疱性关节骨炎(园崎综合征):一例罕见病例报告。
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引用本文的文献

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What Is New and What Is Next for SAPHO Syndrome Management: A Narrative Review.SAPHO综合征管理的新进展与未来方向:一篇叙述性综述
J Clin Med. 2025 Feb 18;14(4):1366. doi: 10.3390/jcm14041366.
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Efficacy of guselkumab in a subpopulation with pustulotic arthro-osteitis through week 52: an exploratory analysis of a phase 3, randomized, double-blind, placebo-controlled study in Japanese patients with palmoplantar pustulosis.至52周时古塞库单抗在脓疱性关节骨炎亚组中的疗效:一项针对日本掌跖脓疱病患者的3期随机双盲安慰剂对照研究的探索性分析
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):2318-2329. doi: 10.1111/jdv.16355. Epub 2020 May 15.