Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo 183-8524, Japan.
Mod Rheumatol Case Rep. 2023 Jun 19;7(2):488-490. doi: 10.1093/mrcr/rxad016.
Pustulotic arthro-osteitis (PAO) is an osteoarticular comorbidity of palmoplantar pustulosis, a chronic, recurrent, inflammatory skin disease presenting with erythema, scales, and pustules on the palms and soles. Palmoplantar pustulosis is one of the most common skin diseases in Japan and is accompanied by PAO in 10-30% of patients. PAO often involves anterior chest wall lesions, but vertebral involvement is uncommon. The present report describes a case of PAO in which the initial manifestation was only non-bacterial vertebral osteitis, with palmoplantar pustulosis developing 8 months after its onset. A patient with vertebral osteitis of unknown aetiology should be followed up and examined periodically for skin problems, which may provide a clue to the presence of PAO.
脓疱性关节炎-骨炎（PAO）是掌跖脓疱病的一种关节骨骼并发症，掌跖脓疱病是一种慢性、复发性、炎症性皮肤病，表现为手掌和脚底出现红斑、鳞屑和脓疱。掌跖脓疱病是日本最常见的皮肤病之一，10-30%的患者伴有 PAO。PAO 常累及前胸壁病变，但椎体受累并不常见。本报告描述了一例 PAO 病例，其初始表现仅为非细菌性椎体骨炎，发病 8 个月后出现掌跖脓疱病。对于病因不明的椎体骨炎患者，应进行随访，并定期检查皮肤问题，这可能为 PAO 的存在提供线索。
