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印度南部一家三级护理医院职业与接触性皮炎诊所的斑贴试验结果:一项回顾性研究

Patch Test Results from an Occupational and Contact Dermatitis Clinic in a Tertiary Care Hospital of Southern India: A Retrospective Study.

作者信息

Sadagopan Kumaravel, Kalappan Deepa, Sivaprakasam Nirmala

机构信息

Professor, Department of Dermatology, Madras Medical College, Chennai, Tamil Nadu, India.

Assistant Professor, Department of Dermatology, Madras Medical College, Chennai, Tamil Nadu, India.

出版信息

J Clin Diagn Res. 2017 Aug;11(8):WC11-WC14. doi: 10.7860/JCDR/2017/26391.10349. Epub 2017 Aug 1.

Abstract

INTRODUCTION

Occupational contact dermatitis, accounting for 95% of cases of occupational dermatoses, is the most common occupational skin disease.

AIM

To find out the various allergens in different occupational and environmental settings causing contact allergy, from our patients presented with contact dermatitis.

MATERIALS AND METHODS

It was a retrospective study from the data in hospital outpatient register over one year period, which includes patients with age ranging from 11 years to 73 years. Patch test was done with total of 24 allergens from Indian standard battery and Indian standard series and with materials suspected to cause contact allergy. Result was expressed in terms of percentage.

RESULTS

Contact dermatitis constitutes about 0.75% of total dermatological cases in our Dermatology Outpatient Department. A total of 358 contact dermatitis were included in this study with M:F ratio 2.25:1 and majority of the cases in the age group of 26-55 years. Out of 358 cases, 157 cases were positive to at least one allergen. Building construction workers constitute about 35.75% (128 cases) of total contact dermatitis cases, among which potassium dichromate (39 out of 57) is the most common allergen, followed by nickel (31) and cobalt (28). In other occupations, contact allergy to parthenium, hair dye, foot wear, paint, , turmeric, detergents and cosmetics were also present in significant number and none was positive for vegetables, dettol, kerosene and native medication.

CONCLUSION

This study gives an idea about the common occupation and population who are prone to develop contact dermatitis in our environmental setting and also about the most common sensitizers involved in various occupation and environment.

摘要

引言

职业性接触性皮炎占职业性皮肤病病例的95%,是最常见的职业性皮肤病。

目的

从我院接触性皮炎患者中,找出不同职业和环境中引起接触性过敏的各种过敏原。

材料与方法

这是一项回顾性研究,数据来源于医院门诊登记处一年期间的数据,包括年龄在11岁至73岁之间的患者。采用印度标准系列中的24种过敏原以及疑似引起接触性过敏的物质进行斑贴试验。结果以百分比表示。

结果

接触性皮炎占我院皮肤科门诊总病例数的约0.75%。本研究共纳入358例接触性皮炎患者,男女比例为2.25:1,大多数病例年龄在26 - 55岁之间。在358例病例中,157例至少对一种过敏原呈阳性反应。建筑工人占接触性皮炎总病例数的约35.75%(128例),其中重铬酸钾(57例中有39例)是最常见的过敏原,其次是镍(31例)和钴(28例)。在其他职业中,对银胶菊、染发剂、鞋类、油漆、姜黄、洗涤剂和化妆品的接触性过敏也大量存在,而对蔬菜、滴露、煤油和天然药物均无阳性反应。

结论

本研究揭示了在我们所处环境中易患接触性皮炎的常见职业和人群,以及不同职业和环境中涉及的最常见致敏原。

相似文献

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Patch Test as a Diagnostic Tool in Hand Eczema.斑贴试验作为手部湿疹的诊断工具
J Clin Diagn Res. 2016 Nov;10(11):WC04-WC07. doi: 10.7860/JCDR/2016/23994.8884. Epub 2016 Nov 1.

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