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儿童脑脓肿:一种罕见但严重的感染。

Brain Abscess in Children: A Rare but Serious Infection.

作者信息

Sahbudak Bal Zumrut, Eraslan Cenk, Bolat Elif, Avcu Gulhadiye, Kultursay Nilgun, Ozkinay Ferda, Kurugol Zafer, Vardar Fadil

机构信息

1 Medical School of Ege University, Bornova, Izmir, Turkey.

出版信息

Clin Pediatr (Phila). 2018 May;57(5):574-579. doi: 10.1177/0009922817733301. Epub 2017 Oct 3.

Abstract

Brain abscess is a rare disease in childhood requiring prompt medical and/or surgical treatment. The objective was to review presentation, management, and outcome of brain abscess in children. We reviewed the clinical and radiological features and outcomes of 18 children (10 females, 8 males), with a median age of 48 months (range 1-182), that presented with brain abscesses and admitted to a tertiary pediatric infectious department between December 2010 and January 2017. One (5.5%) patient underwent craniotomy and 14 (77.7%) had burr hole aspirations. The most common localization was the frontal lobe (33.3%). The survival rate was 94.4%, and long-term neurological sequelae affected 27.7% of the patients. Empiric treatment choices require knowledge of common pathogens and local resistance. The most predominant infections were still upper respiratory infections. Clinicians may treat the children with appropriate choice and duration of antibiotic treatment for upper respiratory tract infections.

摘要

脑脓肿在儿童中是一种罕见疾病,需要及时进行药物和/或手术治疗。目的是回顾儿童脑脓肿的临床表现、治疗及预后。我们回顾了2010年12月至2017年1月间收治于一家三级儿科感染科的18例脑脓肿患儿(10例女性,8例男性)的临床、影像学特征及预后,这些患儿的中位年龄为48个月(范围1 - 182个月)。1例(5.5%)患者接受了开颅手术,14例(77.7%)进行了钻孔抽吸。最常见的病变部位是额叶(33.3%)。生存率为94.4%,27.7%的患者有长期神经后遗症。经验性治疗选择需要了解常见病原体及局部耐药情况。最主要的感染仍是上呼吸道感染。临床医生可为患有上呼吸道感染的儿童选择合适的抗生素治疗并确定疗程。

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