Lee Heesun, Park Jun-Bean, Choi Sae Won, Yoon Yeonyee E, Park Hyo Eun, Lee Sang Eun, Lee Seung-Pyo, Kim Hyung-Kwan, Cho Hyun-Jai, Choi Su-Yeon, Lee Hae-Young, Choi Jonghyuk, Lee Young-Joon, Kim Yong-Jin, Cho Goo-Yeong, Choi Jinwook, Sohn Dae-Won
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic Of Korea.
Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Republic Of Korea.
JMIR Mhealth Uhealth. 2017 Oct 2;5(10):e127. doi: 10.2196/mhealth.7058.
Despite the advances in the diagnosis and treatment of heart failure (HF), the current hospital-oriented framework for HF management does not appear to be sufficient to maintain the stability of HF patients in the long term. The importance of self-care management is increasingly being emphasized as a promising long-term treatment strategy for patients with chronic HF.
The objective of this study was to evaluate whether a new information communication technology (ICT)-based telehealth program with voice recognition technology could improve clinical or laboratory outcomes in HF patients.
In this prospective single-arm pilot study, we recruited 31 consecutive patients with chronic HF who were referred to our institute. An ICT-based telehealth program with voice recognition technology was developed and used by patients with HF for 12 weeks. Patients were educated on the use of this program via mobile phone, landline, or the Internet for the purpose of improving communication and data collection. Using these systems, we collected comprehensive data elements related to the risk of HF self-care management such as weight, diet, exercise, medication adherence, overall symptom change, and home blood pressure. The study endpoints were the changes observed in urine sodium concentration (uNa), Minnesota Living with Heart Failure (MLHFQ) scores, 6-min walk test, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) as surrogate markers for appropriate HF management.
Among the 31 enrolled patients, 27 (87%) patients completed the study, and 10 (10/27, 37%) showed good adherence to ICT-based telehealth program with voice recognition technology, which was defined as the use of the program for 100 times or more during the study period. Nearly three-fourths of the patients had been hospitalized at least once because of HF before the enrollment (20/27, 74%); 14 patients had 1, 2 patients had 2, and 4 patients had 3 or more previous HF hospitalizations. In the total study population, there was no significant interval change in laboratory and functional outcome variables after 12 weeks of ICT-based telehealth program. In patients with good adherence to ICT-based telehealth program, there was a significant improvement in the mean uNa (103.1 to 78.1; P=.01) but not in those without (85.4 to 96.9; P=.49). Similarly, a marginal improvement in MLHFQ scores was only observed in patients with good adherence (27.5 to 21.4; P=.08) but not in their counterparts (19.0 to 19.7; P=.73). The mean 6-min walk distance and NT-proBNP were not significantly increased in patients regardless of their adherence.
Short-term application of ICT-based telehealth program with voice recognition technology showed the potential to improve uNa values and MLHFQ scores in HF patients, suggesting that better control of sodium intake and greater quality of life can be achieved by this program.
尽管心力衰竭(HF)的诊断和治疗取得了进展,但当前以医院为导向的HF管理框架似乎不足以长期维持HF患者的稳定性。自我护理管理的重要性日益受到重视,被视为慢性HF患者一种有前景的长期治疗策略。
本研究的目的是评估一种基于新信息通信技术(ICT)并带有语音识别技术的远程医疗计划是否能改善HF患者的临床或实验室结果。
在这项前瞻性单臂试点研究中,我们连续招募了31名转诊至我院的慢性HF患者。开发了一种基于ICT并带有语音识别技术的远程医疗计划,供HF患者使用12周。通过手机、固定电话或互联网对患者进行该计划使用方法的培训,以改善沟通和数据收集。利用这些系统,我们收集了与HF自我护理管理风险相关的综合数据元素,如体重、饮食、运动、药物依从性、总体症状变化和家庭血压。研究终点是观察到的尿钠浓度(uNa)、明尼苏达心力衰竭生活质量量表(MLHFQ)评分、6分钟步行试验以及脑钠肽前体N末端(NT-proBNP)的变化,这些作为HF适当管理的替代指标。
在31名登记患者中,27名(87%)患者完成了研究,10名(10/27,37%)患者对基于ICT并带有语音识别技术的远程医疗计划表现出良好依从性,良好依从性定义为在研究期间使用该计划100次或更多次。近四分之三的患者在入组前因HF至少住院一次(20/27,74%);14名患者曾住院1次,2名患者曾住院2次,4名患者曾住院3次或更多次。在整个研究人群中,基于ICT的远程医疗计划实施12周后,实验室和功能结局变量没有显著的间隔变化。在对基于ICT的远程医疗计划依从性良好的患者中,平均uNa有显著改善(从103.1降至78.1;P = 0.01),而依从性不佳的患者则没有(从85.4升至96.9;P = 0.49)。同样,仅在依从性良好的患者中观察到MLHFQ评分有轻微改善(从27.5降至21.4;P = 0.08),而依从性不佳的患者则没有(从19.0升至19.7;P = 0.73)。无论依从性如何,患者的平均6分钟步行距离和NT-proBNP均未显著增加。
基于ICT并带有语音识别技术的远程医疗计划的短期应用显示出改善HF患者uNa值和MLHFQ评分的潜力,表明该计划可实现更好的钠摄入控制和更高的生活质量。