在一名对血小板产生耐受的再生障碍性贫血患者中，使用交叉配型相容的血小板成功实施手术。
Successful surgical procedure in a patient of aplastic anemia with platelet refractoriness, using cross-match compatible platelets.
作者信息
Chakrabarty Ritam, Das Sudipta Sekhar
机构信息
Department of Transfusion Medicine, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
出版信息
Asian J Transfus Sci. 2017 Jul-Dec;11(2):192-194. doi: 10.4103/ajts.AJTS_115_16.
This case marks the beginning of issuing cross-matched platelet products in Eastern India. A known case of aplastic anemia, on regular transfusion support, now presented with obstructed ventral periumbilical hernia requiring urgent surgical intervention. Platelet count at presentation was 13,000/μL. Platelet cross-matching was done by solid phase method. Ten units of random donor platelets were crossmatched. Five units were compatible and transfused. Counts rose to 84,000/μL after 1 h. Surgery was completed successfully. Thus, 50% units were compatible. This indicates possible underlying alloimmunization. Rapid count rise enabled completion of this urgent surgery. This rapid rise of platelet count would not have been possible without cross matching. We conclude that platelet cross matching is a powerful tool for alloimmunized patients.
该病例标志着印度东部开始发放交叉配型的血小板制品。一名已知的再生障碍性贫血患者，长期接受输血支持，现出现脐周腹疝梗阻，需要紧急手术干预。就诊时血小板计数为13,000/μL。采用固相法进行血小板交叉配型。对10单位随机供者血小板进行交叉配型。5单位相匹配并进行了输注。1小时后计数升至84,000/μL。手术成功完成。因此，50%的单位相匹配。这表明可能存在潜在的同种免疫。计数快速上升使得该紧急手术得以完成。如果没有交叉配型，血小板计数不可能如此快速上升。我们得出结论，血小板交叉配型对于同种免疫患者是一种有力的工具。
Zotero 插件