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预防性卡唑洛尔治疗对公猪采精过程中应激反应的影响

[The effect of preventative carazolol treatment on stress reactions in boars during semen collection].

作者信息

Steinmann C, Perez E, Scholl E

机构信息

Klinik für kleine Klauentiere und forensische Medizin und Ambulatorischen Klinik Tierärztlichen Hochschule Hannover.

出版信息

Tierarztl Prax Suppl. 1988;3:101-6.

PMID:2897136
Abstract

The effect of the beta adrenoceptor blocking agent carazolol on heart and circulatory system, on blood values of the acid-base-equilibrium and on plasma enzymes such as creatine-kinase (CK) and aspartate-amino-transferase (ASAT) was investigated in four clinical healthy boars of the German Landrace and four boars of the Piétrain race before, during and after ejaculation at the phantom. The heart rate during semen collection increased less with treatment than it did without it. The relative diastolic time during exertion was prolonged by carazolol in those boars, which also without pharmacological influence had a very short relative diastolic time. By carazolol injection the systolic blood pressure could be decreased most in those boars, which without treatment had the highest rise of systolic blood pressure during semen collection. Furthermore it was shown, that the highest lactate values, which were found in some boars of the Piétrain race, were reduced most by the influence of carazolol. The blood values of the acid-base-equilibrium were highly negative correlated with the lactate values and changed according to them. The enzyme activities (CK and ASAT) 24 h after semen collection were not influenced by carazolol. Individual differences from boar to boar were evident in all examined parameters and were independent of the effects of carazolol treatment.

摘要

在德国长白猪的4头临床健康公猪和皮特兰猪的4头公猪身上,研究了β肾上腺素能受体阻滞剂卡拉洛尔对心脏和循环系统、酸碱平衡血液值以及肌酸激酶(CK)和天冬氨酸氨基转移酶(ASAT)等血浆酶的影响,研究时间为在假台畜上采精前、采精期间和采精后。与未治疗相比,治疗过程中采精时的心率增加较少。在那些即使没有药理影响相对舒张期也很短的公猪中,卡拉洛尔可延长其运动时的相对舒张期。注射卡拉洛尔后,在那些未治疗时采精期间收缩压升高幅度最大的公猪中,收缩压下降最多。此外,研究表明,在一些皮特兰猪公猪中发现的最高乳酸值,受卡拉洛尔影响下降最多。酸碱平衡的血液值与乳酸值高度负相关,并随乳酸值变化而变化。采精后24小时的酶活性(CK和ASAT)不受卡拉洛尔影响。在所有检测参数中,公猪之间的个体差异明显,且与卡拉洛尔治疗效果无关。

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