Geronikolou Styliani A, Bacopoulou Flora, Cokkinos Dennis
Clinical, Translational and Experimental Surgery Research Centre, Biomedical Research Foundation of Academy of Athens, 4 Soranou Ephessiou Street, 11527, Athens, Greece.
Center for Adolescent Medicine and UNESCO Chair on Adolescent Health Care, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, "Aghia Sophia" Children's Hospital, 3 Thivon Street, 11527, Athens, Greece.
Adv Exp Med Biol. 2017;987:291-299. doi: 10.1007/978-3-319-57379-3_26.
Limited data are available on the body composition of adolescent women with polycystic ovary syndrome (PCOS). The aim of this study was to examine differences in body composition indices of metabolism, homeostasis and inflammation, between Greek adolescent females suffering from PCOS and age- and body mass index (BMI)-matched non-PCOS controls. Thirteen PCOS patients and nine non-PCOS controls, aged 13-24 years participated in this cross-sectional study. Study participants underwent assessment by a novel dual frequency bioimpedance device (BIA-ACC). The following body composition indices were measured in each adolescent: extra cellular water (ECW) as inflammation marker, total body water (TBW) as homeostasis marker, extracellular mass to body cell mass ratio (ECM/BCM), fat mass (FM), fat-free mass (FFM) and intracellular water (ICW) as markers of body mass composition and metabolism. Non-linear analysis showed no statistically significant differences in the body composition characteristics between PCOS patients and controls. Further studies with larger sample sizes are needed to confirm whether adolescents with PCOS actually have similar body composition profile with their non-PCOS peers.
关于多囊卵巢综合征（PCOS）青春期女性的身体成分数据有限。本研究的目的是检查患有PCOS的希腊青春期女性与年龄和体重指数（BMI）匹配的非PCOS对照组在代谢、内稳态和炎症的身体成分指标上的差异。13名PCOS患者和9名非PCOS对照组，年龄在13 - 24岁之间，参与了这项横断面研究。研究参与者通过一种新型双频生物阻抗设备（BIA - ACC）进行评估。在每个青少年中测量了以下身体成分指标：作为炎症标志物的细胞外液（ECW）、作为内稳态标志物的总体液（TBW）、细胞外质量与身体细胞质量比（ECM/BCM）、脂肪量（FM）、去脂体重（FFM）和作为身体质量组成与代谢标志物的细胞内液（ICW）。非线性分析显示PCOS患者和对照组在身体成分特征上无统计学显著差异。需要进一步进行更大样本量的研究，以确认患有PCOS的青少年实际上是否与其非PCOS同龄人具有相似的身体成分特征。
