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二级医疗机构慢性疼痛患者中精神障碍的十年患病率:一项基于登记数据的队列研究。

Ten-year prevalence of mental disorders in patients presenting with chronic pain in secondary care: A register linkage cohort study.

机构信息

Research Unit in Mental Health, Institute for Regional Health Services, University of Southern Denmark, Aabenraa, Denmark.

Pain Research Group, Pain Centre South, Odense University Hospital, Denmark.

出版信息

Eur J Pain. 2018 Feb;22(2):346-354. doi: 10.1002/ejp.1124. Epub 2017 Oct 3.

Abstract

BACKGROUND

Prevalence rates of mental disorders in patients with chronic pain vary and may be overestimated when assessed by screening instruments only. Objectives were to estimate the 10-year prevalence of different mental disorders diagnosed by psychiatrists in patients with chronic pain compared with the Danish general population.

METHODS

Patients (n = 7197) consulted in the interdisciplinary Pain Clinic South at Odense University Hospital, Denmark, from 2005 to 2015 were included. Data from the Pain Clinic were linked to the Danish National Patient Register-Psychiatry and the Danish Civil Registration System. Age and gender standardized prevalence ratios (SPR) were calculated.

RESULTS

In all, 17.8% of patients with chronic pain had been diagnosed with a mental disorder. The most frequent diagnoses were adjustment disorders (subcategory of anxiety disorders) (8.9%), depression (6.1%), personality disorders (3.8%), and substance abuse disorders (3.5%). Women and men with chronic pain had higher rates of anxiety disorders (SPR 3.1; 95% CI 2.9-3.4) and depression (SPR 2.5; 95% CI 2.3-2.8), whereas men had higher rates of substance abuse disorders (SPR 1.6; 95% CI 1.3-1.9) than found for the general population.

CONCLUSIONS

Although depression and anxiety were noted more frequently among patients with chronic pain than the general population, prevalence rates were lower than previously reported. The most frequent diagnoses were adjustment disorders.

SIGNIFICANCE

Prevalence rates of anxiety and depression diagnosed by psychiatrists in patients with chronic pain were found to be lower than previous findings using screening instruments. Adjustment disorders were the most frequent disorders diagnosed, as this study is the first to investigate.

摘要

背景

慢性疼痛患者的精神障碍患病率各不相同,仅通过筛查工具评估可能会高估。目的是评估与丹麦普通人群相比,慢性疼痛患者中由精神科医生诊断的不同精神障碍的 10 年患病率。

方法

本研究纳入了 2005 年至 2015 年在丹麦奥胡斯大学医院南区跨学科疼痛诊所就诊的 7197 名患者。疼痛诊所的数据与丹麦国家患者登记-精神病学和丹麦民事登记系统相关联。计算了年龄和性别标准化患病率比 (SPR)。

结果

所有慢性疼痛患者中有 17.8%被诊断为精神障碍。最常见的诊断是适应障碍(焦虑障碍的亚类)(8.9%)、抑郁(6.1%)、人格障碍(3.8%)和物质滥用障碍(3.5%)。患有慢性疼痛的女性和男性焦虑障碍的发生率更高(SPR 3.1;95%CI 2.9-3.4)和抑郁(SPR 2.5;95%CI 2.3-2.8),而男性物质滥用障碍的发生率更高(SPR 1.6;95%CI 1.3-1.9)比普通人群高。

结论

尽管慢性疼痛患者的抑郁和焦虑发生率高于普通人群,但患病率低于之前的报告。最常见的诊断是适应障碍。

意义

本研究发现,慢性疼痛患者中由精神科医生诊断的焦虑和抑郁患病率低于之前使用筛查工具的研究结果。适应障碍是最常见的诊断障碍,因为这是首次对此进行研究。

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