Li Justin C-H, Fong Warren, Wijaya Limin, Leung Ying Y
Department of Rheumatology & Immunology, Singapore General Hospital, Singapore, Singapore.
Li Ka Shing, Faculty of Medicine, the University of Hong Kong, Hong Kong, China.
Int J Rheum Dis. 2018 Jan;21(1):352-355. doi: 10.1111/1756-185X.13195. Epub 2017 Oct 2.
Tuberculosis (TB) infection is the endemic in Asia-Pacific region. Miliary TB is a disseminated form which may present similarly as autoimmune conditions. Here we describe a 17-year-old girl who had miliary TB with manifestations mimicking new-onset systemic lupus erythematosus (SLE) including oral ulcers, serositis, cytopenia, proteinuria and raised autoantibody titers. Complex associations between SLE and TB are highlighted. High index of clinical suspicion for TB infection is needed upon presentations resembling immune diseases like SLE.
结核病(TB)感染在亚太地区呈地方性流行。粟粒性肺结核是一种播散性形式,其表现可能与自身免疫性疾病相似。在此,我们描述一名17岁女孩,她患有粟粒性肺结核,其表现类似于新发系统性红斑狼疮(SLE),包括口腔溃疡、浆膜炎、血细胞减少、蛋白尿和自身抗体滴度升高。强调了SLE与TB之间的复杂关联。当出现类似SLE等免疫疾病的症状时,需要对TB感染有高度的临床怀疑。