Siegel E, Cations M, Wright C, Naganathan V, Deutsch A, Aerts L, Brodaty H
Henry Brodaty, Dementia Collaborative Research Centre, AGSM Building, School of Psychiatry, Faculty of Medicine, UNSW Australia, UNSW Sydney NSW 2052, Australia, P: +61 2 9385 2585, F: +61 2 9385 2200, E:
J Nutr Health Aging. 2017;21(8):874-886. doi: 10.1007/s12603-016-0851-6.
Oral diseases and conditions are prevalent among older people with dementia and cognitive impairment. While many interventions have been advocated for use in this population, evidence for their effectiveness is unclear. Our objective was to review systematically the content and effectiveness of interventions and implementation strategies used to improve or maintain the oral health of people with dementia or cognitive impairment.
Original studies published in English at any time until January 2015 were identified through electronic searches of the Medline, Embase, CINAHL, Scopus and Cochrane databases and hand searches of eligible studies and relevant reviews. Two investigators independently abstracted study characteristics and assessed the methodological quality of eligible studies. Results were presented as a narrative review because significant heterogeneity among included studies precluded a meta-analysis.
The 18 included studies varied considerably in terms of size, scope and focus. Only two studies were identified that had been designed specifically for and examined exclusively in people with dementia or cognitive impairment. All studies were in residential care; none was population-based. While several studies reported positive effects, a number of methodological weaknesses were identified and the overall quality of included studies was poor. The specific outcomes targeted varied across studies but most studies focused almost exclusively on proximal clinical oral health outcomes such as levels of dental or denture plaque. Attempts to measure intervention integrity were limited and there was usually little or no effort to evaluate intervention effects over a sustained period.
There is a lack of high quality evidence to support the effectiveness of oral health interventions and implementation strategies for older people with dementia or cognitive impairment. More rigorous, large scale research is needed in this area. Recommendations are provided to improve the overall quality of evaluation in this area. Emphasis must be placed on developing evidence-based, achievable and sustainable oral health strategies if the needs of people with dementia and cognitive impairment are to be met into the future.
口腔疾病和状况在患有痴呆症和认知障碍的老年人中普遍存在。虽然已经提倡在这一人群中使用多种干预措施,但其有效性的证据尚不清楚。我们的目的是系统回顾用于改善或维持痴呆症或认知障碍患者口腔健康的干预措施及实施策略的内容和有效性。
通过对Medline、Embase、CINAHL、Scopus和Cochrane数据库进行电子检索,以及对符合条件的研究和相关综述进行手工检索,确定截至2015年1月随时以英文发表的原始研究。两名研究人员独立提取研究特征并评估符合条件研究的方法学质量。由于纳入研究之间存在显著异质性,无法进行荟萃分析,因此结果以叙述性综述的形式呈现。
纳入的18项研究在规模、范围和重点方面差异很大。仅确定了两项专门为痴呆症或认知障碍患者设计并仅在该人群中进行研究的研究。所有研究均在机构护理环境中进行;没有基于人群的研究。虽然有几项研究报告了积极效果,但也发现了一些方法学上的弱点,纳入研究的总体质量较差。不同研究针对的具体结果各不相同,但大多数研究几乎完全集中在近端临床口腔健康结果上,如牙菌斑或假牙菌斑水平。衡量干预完整性尝试有限,而且通常很少或根本没有努力评估干预措施在一段时间内的效果。
缺乏高质量证据支持针对患有痴呆症或认知障碍的老年人的口腔健康干预措施及实施策略的有效性。该领域需要更严格、大规模的研究。本文提供了相关建议以提高该领域评估的整体质量。如果要满足痴呆症和认知障碍患者未来的需求,必须强调制定基于证据、可行且可持续的口腔健康策略。