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阿扎尔地区部分湖泊中硫化物粉质胶体的特性及生物活性化合物含量的测定

CHARACTERIZATION OF SULPHIDE SILT PE-LOIDS IN SOME LAKES WITHIN ADJARA REGION AND DETERMINATION OF THE BIOLOGICALLY ACTIVE COMPOUNDS CONTENT.

作者信息

Masiukovichi T, Jokhadze M, Murtazashvili T, Bakuridze A

机构信息

Tbilisi State Medical University, Department of Pharmaceutical and Toxicological Chemistry; Department of Pharmaceutical Technology; LEPL Levan Samkharauli National Forensics Bureau, Tbilisi, Georgia.

出版信息

Georgian Med News. 2017 Sep(270):115-120.

PMID:28972495
Abstract

Medicinal muds, so called Peloids in the last decade attract attention in many countries as effective means for the treatment- preventive, and perfumery-cosmetic purposes. It has been established that the possibilities of this formation of nature are not limited to the many-year experience of the mankind. In terms of further improvement of the human social sphere, nowadays peloids are referred to as XXI century material. The aim of the research was to study the physical-chemical characteristics, such as: humidity, pH, ash content, bulk (volumetric) density and organoleptic properties of sulphide silt peloids of some Adjara region lakes, as well as to determine the content of mineral and organic compounds (humic and organic acids). The objects of the study were the sulphide silt peloids of some Adjara region lakes: Mtsvane, Gasaliani, Shratiani, Nurigeli, Ardagani and Niphi. The main good quality indicators of the sulphide silt peloids have been determined according to the methods described in the State Pharmacopoeia XI. The mineral and organic compounds in the research objects have been determined using the modern instrumental methods of analysis described in the literature. Based on the performed studies, the main physical-chemical characteristics of sulphide silt peloids of some Adjara region lakes (Mtsvane, Gasaliani, Shratiani, Nurigeli, Ardagani and Niphi) have been studied and their mineral contents (Ca-Na Feldspar, K Feldspar, Ca- Montmorillonite, Hematite, Quartz, Magnetite, Chlorite) determined. By the spectrophotometric and gravimetric methods of analysis there is established, that the sulphide silt peloids of the lakes Ardagani (1,22%), Niphi (1,72%) and Gasaliani (1,33%) are distinguished by relatively higher content of humic acids. By the Gas Chromatography-Mass Spectrometry - method of analysis, in the study objects there is established the content of complex ethers of the following organic acids: Stearic, Palmitic, Caprylic, Myristic, Valeric, Lauric, Oxalic, Phthalic and Fumaric acids.

摘要

药用泥浆,在过去十年中被称为泥类物质,在许多国家作为治疗、预防以及香料化妆品用途的有效手段而受到关注。已经确定,这种天然形成物的可能性并不局限于人类多年的经验。就人类社会领域的进一步改善而言,如今泥类物质被称为21世纪的材料。该研究的目的是研究一些阿扎尔地区湖泊的硫化物淤泥类物质的物理化学特性,如湿度、pH值、灰分含量、堆积(体积)密度和感官特性,以及确定矿物和有机化合物(腐殖酸和有机酸)的含量。研究对象是一些阿扎尔地区湖泊的硫化物淤泥类物质:姆茨瓦内湖、加萨利亚尼湖、什拉蒂亚尼湖、努里盖利湖、阿尔达加尼湖和尼菲湖。硫化物淤泥类物质的主要质量指标已根据《国家药典XI》中描述的方法确定。研究对象中的矿物和有机化合物已使用文献中描述的现代仪器分析方法进行测定。基于所进行的研究,对一些阿扎尔地区湖泊(姆茨瓦内湖、加萨利亚尼湖、什拉蒂亚尼湖、努里盖利湖、阿尔达加尼湖和尼菲湖)的硫化物淤泥类物质的主要物理化学特性进行了研究,并确定了它们的矿物含量(钙钠长石、钾长石、钙蒙脱石、赤铁矿、石英、磁铁矿、绿泥石)。通过分光光度法和重量分析法确定,阿尔达加尼湖(1.22%)、尼菲湖(1.72%)和加萨利亚尼湖(1.33%)的硫化物淤泥类物质的腐殖酸含量相对较高。通过气相色谱-质谱分析法,在研究对象中确定了以下有机酸的复合醚含量:硬脂酸、棕榈酸、辛酸、肉豆蔻酸、戊酸、月桂酸、草酸、邻苯二甲酸和富马酸。

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