O'Donoghue Cristina, Quinn Gwendolyn P, Lee M Catherine
From the Division Surgical Oncology, Department of Surgery, Rush University Medical Center, Chicago, Illinois, Department of Oncologic Sciences, Health Outcomes and Behavior, Moffitt Cancer Center, The University of South Florida, Morsani College of Medicine, Tampa, Florida, and the Comprehensive Breast Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
South Med J. 2017 Oct;110(10):621-626. doi: 10.14423/SMJ.0000000000000704.
As more young women survive breast cancer, fertility preservation (FP) is an important component of care. This review highlights the importance of early pretreatment referral, reviews the risks of infertility associated with breast cancer treatment, and defines existing and emerging techniques for FP. The techniques reviewed include ovarian suppression, embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation and transplantation. The barriers women face, such as not being appropriately referred and the costs of treatment, also are addressed. Multidisciplinary, patient-centered care is essential to discussing FP with patients with breast cancer and ensuring appropriate care that includes quality of life in survivorship.
随着越来越多的年轻女性在乳腺癌中存活下来，生育力保存（FP）成为护理的重要组成部分。本综述强调了预处理早期转诊的重要性，回顾了与乳腺癌治疗相关的不孕风险，并定义了现有的和新兴的生育力保存技术。所综述的技术包括卵巢抑制、胚胎冷冻保存、卵母细胞冷冻保存以及卵巢组织冷冻保存和移植。还讨论了女性面临的障碍，如未得到适当转诊和治疗费用等问题。多学科、以患者为中心的护理对于与乳腺癌患者讨论生育力保存并确保包括生存质量在内的适当护理至关重要。
